Thoracoabdominal aortic aneurysm in Cogan’s syndrome

Arteriogram demonstrating aneurysmal visceral aortic segment and associated critical bilateral renal artery stenoses (arrows ).

A, Non-contrast computed tomography scan of type III thoracoabdominal aneurysm. B, Corresponding arteriogram demonstrates focal nature of the largest part of the aneurysm in the distal descending thoracic aorta. C, Abdominal aortic phase of arteriogram demonstrating severe proximal left renal artery stenosis (arrow ) and diffusely aneurysmal infrarenal aorta.

A, Low-power photomicrograph of aorta, showing marked destruction of medial elastic tissue (original magnification 25×; elastic van Gieson). B, Medium-power photomicrograph of the medial-adventitial interface of the arterial specimen showing a dense inflammatory infiltrate consisting of mostly lymphocytes. Fibrosis and neovascularization is also present (original magnification 100×; hematoxylin and eosin).