Journal of Vascular Surgery
Volume 52, Issue 6 , Pages 1608-1615, December 2010

Endothelial cells are susceptible to rapid siRNA transfection and gene silencing ex vivo

  • Nicholas D. Andersen, MD

      Affiliations

    • Department of Vascular Surgery Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Mass
    • ,
  • Atish Chopra

      Affiliations

    • Department of Vascular Surgery Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Mass
    • ,
  • Thomas S. Monahan, MD

      Affiliations

    • Department of Vascular Surgery Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Mass
    • ,
  • Junaid Y. Malek, MD

      Affiliations

    • Department of Vascular Surgery Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Mass
    • ,
  • Monica Jain, BS

      Affiliations

    • Boston University School of Medicine, Boston, Mass
    • ,
  • Leena Pradhan, PhD

      Affiliations

    • Department of Vascular Surgery Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Mass
    • ,
  • Christiane Ferran, MD, PhD

      Affiliations

    • Department of Vascular Surgery Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Mass
    • ,
  • Frank W. LoGerfo, MD

      Affiliations

    • Department of Vascular Surgery Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Mass
    • Corresponding Author InformationReprint requests: Frank W. LoGerfo, MD, Beth Israel Deaconess Medical Center, LMOB, Ste. 3B, 110 Francis St., Boston, MA 02115

Received 3 April 2010; accepted 27 June 2010. published online 01 September 2010.

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 Supported by National Institutes of Health R01 Grants HL021796, HL086741 (to CF and FL), and HL080130 (to CF), National Institutes of Health T32 Harvard-Longwood Research Training in Vascular Surgery Grant HL007734 (to TM and JM), a Howard Hughes Medical Institute Research Training Fellowship for Medical Students (to NA), The von Liebig Foundation (to ID, FE, MJ, LP, and FL), and the Royal College of Surgeons in Ireland Annual Appeal Alumni Research Fund (to AC).

 Competition of interest: none.

 The editors and reviewers of this article have no relevant financial relationships to disclose per the JVS policy that requires reviewers to decline review of any manuscript for which they may have a competition of interest.

PII: S0741-5214(10)01674-5

doi:10.1016/j.jvs.2010.06.169

Journal of Vascular Surgery
Volume 52, Issue 6 , Pages 1608-1615, December 2010

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