Evaluation of peripheral atherosclerosis: A comparative analysis of angiography and intravascular ultrasound imaging

Inter-rater concordance is shown among angiographic examiners for determining maximal percent stenosis. The open circles represent actual measured data points among examiners, the solid black represents the linear regression through those points, and the hashed red line represents the 95% confidence interval.

An example of angiographic and intravascular ultrasound (IVUS) analysis is shown. A, The large white arrow in the angiogram marks the area for analysis. This was interpreted as a 30% stenosis based on the angiogram. B, IVUS grey scale imaging through this area is illustrated. The yellow line marks the internal elastic lamina, and the red line marks the external elastic lamina. By IVUS, this represents a 76% area stenosis. C, In this example of virtual histology analysis, the dark and light green shades denote fibrous plaque, which accounts for the majority of this lesion, the red areas represent necrotic plaque, and white areas denote calcium.