Journal of Vascular Surgery
Volume 51, Issue 1 , Pages 155-164 , January 2010

Long-term patency of small-diameter vascular graft made from fibroin, a silk-based biodegradable material

  • Soichiro Enomoto, MD, PhD

      Affiliations

    • Department of Cardiovascular Medicine, University of Tokyo Graduate School of Medicine, Tokyo, Japan
  • ,
  • Makoto Sumi, MD, PhD

      Affiliations

    • Department of Cardiovascular Medicine, University of Tokyo Graduate School of Medicine, Tokyo, Japan
    • Department of Vascular Surgery, Jikei University School of Medicine, Tokyo, Japan
  • ,
  • Kan Kajimoto, MD, PhD

      Affiliations

    • Department of Cardiovascular Surgery, Juntendo University School of Medicine, Tokyo, Japan
  • ,
  • Yasumoto Nakazawa, PhD

      Affiliations

    • Department of Biotechnology, Tokyo University of Agriculture and Technology, Tokyo, Japan
  • ,
  • Rui Takahashi, MS

      Affiliations

    • Department of Biotechnology, Tokyo University of Agriculture and Technology, Tokyo, Japan
  • ,
  • Chiyuki Takabayashi, PhD

      Affiliations

    • Laboratory of New Silk Materials, National Institute of Agrobiological Sciences, Okaya, Nagano, Japan
  • ,
  • Tetsuo Asakura, PhD

      Affiliations

    • Department of Biotechnology, Tokyo University of Agriculture and Technology, Tokyo, Japan
  • ,
  • Masataka Sata, MD, PhD

      Affiliations

    • Department of Cardiovascular Medicine, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima, Japan
    • Corresponding Author InformationCorrespondence: Masataka Sata, MD, PhD, Professor and Chairman, Department of Cardiovascular Medicine, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto-cho, Tokushima 770-8503, Japan

Received 20 July 2009 ,Accepted 5 September 2009.

References 

  1. Pektok E, Nottelet B, Tille JC, Gurny R, Kalangos A, Moeller M, et al. Degradation and healing characteristics of small-diameter poly(epsilon-caprolactone) vascular grafts in the rat systemic arterial circulation. Circulation. 2008;118:2563–2570
  2. Daenens K, Schepers S, Fourneau I, Houthoofd S, Nevelsteen A. Heparin-bonded ePTFE grafts compared with vein grafts in femoropopliteal and femorocrural bypasses: 1- and 2-year results. J Vasc Surg. 2009;49:1210–1216
  3. Pawlowski KJ, Rittgers SE, Schmidt SP, Bowlin GL. Endothelial cell seeding of polymeric vascular grafts. Front Biosci. 2004;9:1412–1421
  4. Langer R, Vacanti JP. Tissue engineering. Science. 1993;260:920–926
  5. Sharp MA, Phillips D, Roberts I, Hands L. A cautionary case: the SynerGraft vascular prosthesis. Eur J Vasc Endovasc Surg. 2004;27:42–44
  6. Shin'oka T, Matsumura G, Hibino N, Naito Y, Watanabe M, Konuma T, et al. Midterm clinical result of tissue-engineered vascular autografts seeded with autologous bone marrow cells. J Thorac Cardiovasc Surg. 2005;129:1330–1338
  7. L'Heureux N, Dusserre N, Konig G, Victor B, Keire P, Wight TN, et al. Human tissue-engineered blood vessels for adult arterial revascularization. Nat Med. 2006;12:361–365
  8. L'Heureux N, McAllister TN, de la Fuente LM. Tissue-engineered blood vessel for adult arterial revascularization. N Engl J Med. 2007;357:1451–1453
  9. McAllister TN, Maruszewski M, Garrido SA, Wystrychowski W, Dusserre N, Marini A, et al. Effectiveness of haemodialysis access with an autologous tissue-engineered vascular graft: a multicentre cohort study. Lancet. 2009;373:1440–1446
  10. Altman GH, Diaz F, Jakuba C, Calabro T, Horan RL, Chen J, et al. Silk-based biomaterials. Biomaterials. 2003;24:401–416
  11. Lam KH, Nijenhuis AJ, Bartels H, Postema AR, Jonkman MF, Pennings AJ, et al. Reinforced poly(L-lactic acid) fibres as suture material. J Appl Biomater. 1995;6:191–197
  12. Rossitch E, Bullard DE, Oakes WJ. Delayed foreign-body reaction to silk sutures in pediatric neurosurgical patients. Childs Nerv Syst. 1987;3:375–378
  13. Salthouse TN, Matlaga BF, Wykoff MH. Comparative tissue response to six suture materials in rabbit cornea, sclera, and ocular muscle. Am J Ophthalmol. 1977;84:224–233
  14. Soong HK, Kenyon KR. Adverse reactions to virgin silk sutures in cataract surgery. Ophthalmology. 1984;91:479–483
  15. Altman GH, Horan RL, Lu HH, Moreau J, Martin I, Richmond JC, et al. Silk matrix for tissue engineered anterior cruciate ligaments. Biomaterials. 2002;23:4131–4141
  16. Inouye K, Kurokawa M, Nishikawa S, Tsukada M. Use of Bombyx mori silk fibroin as a substratum for cultivation of animal cells. J Biochem Biophys Methods. 1998;37:159–164
  17. Minoura N, Aiba S, Gotoh Y, Tsukada M, Imai Y. Attachment and growth of cultured fibroblast cells on silk protein matrices. J Biomed Mater Res. 1995;29:1215–1221
  18. Sofia S, McCarthy MB, Gronowicz G, Kaplan DL. Functionalized silk-based biomaterials for bone formation. J Biomed Mater Res. 2001;54:139–148
  19. Okabe M, Ikawa M, Kominami K, Nakanishi T, Nishimune Y. 'Green mice' as a source of ubiquitous green cells. FEBS Lett. 1997;407:313–319
  20. Sata M, Saiura A, Kunisato A, Tojo A, Okada S, Tokuhisa T, et al. Hematopoietic stem cells differentiate into vascular cells that participate in the pathogenesis of atherosclerosis. Nat Med. 2002;8:403–409
  21. Fukuda D, Sata M, Ishizaka N, Nagai R. Critical role of bone marrow angiotensin II type 1 receptor in the pathogenesis of atherosclerosis in apolipoprotein E deficient mice. Arterioscler Thromb Vasc Biol. 2008;28:90–96
  22. Tanaka K, Sata M, Hirata Y, Nagai R. Diverse contribution of bone marrow cells to neointimal hyperplasia after mechanical vascular injuries. Circ Res. 2003;93:783–790
  23. Sahara M, Sata M, Morita T, Nakamura K, Hirata Y, Nagai R. Diverse contribution of bone marrow-derived cells to vascular remodeling associated with pulmonary arterial hypertension and arterial neointimal formation. Circulation. 2007;115:509–517
  24. Grzesiak JJ, Pierschbacher MD, Amodeo MF, Malaney TI, Glass JR. Enhancement of cell interactions with collagen/glycosaminoglycan matrices by RGD derivatization. Biomaterials. 1997;18:1625–1632
  25. He H, Shirota T, Yasui H, Matsuda T. Canine endothelial progenitor cell-lined hybrid vascular graft with nonthrombogenic potential. J Thorac Cardiovasc Surg. 2003;126:455–464
  26. Kaushal S, Amiel GE, Guleserian KJ, Shapira OM, Perry T, Sutherland FW, et al. Functional small-diameter neovessels created using endothelial progenitor cells expanded ex vivo. Nat Med. 2001;7:1035–1040
  27. Matsumura G, Hibino N, Ikada Y, Kurosawa H, Shin'oka T. Successful application of tissue engineered vascular autografts: clinical experience. Biomaterials. 2003;24:2303–2308
  28. Moriya M, Roschzttardtz F, Nakahara Y, Saito H, Masubuchi Y, Asakura T. Rheological properties of native silk fibroins from domestic and wild silkworms, and flow analysis in each spinneret by a finite element method. Biomacromolecules. 2009;10:929–935
  29. Zhao C, Yao J, Masuda H, Kishore R, Asakura T. Structural characterization and artificial fiber formation of Bombyx mori silk fibroin in hexafluoro-iso-propanol solvent system. Biopolymers. 2003;69:253–259
  30. Setzen G, Williams EF. Tissue response to suture materials implanted subcutaneously in a rabbit model. Plast Reconstr Surg. 1997;100:1788–1795
  31. Bucknall TE, Teare L, Ellis H. The choice of a suture to close abdominal incisions. Eur Surg Res. 1983;15:59–66
  32. Sahara M, Sata M, Matsuzaki Y, Tanaka K, Morita T, Hirata Y, et al. Comparison of various bone marrow fractions in the ability to participate in vascular remodeling after mechanical injury. Stem Cells. 2005;23:874–878
  33. Hillebrands JL, Klatter FA, van Dijk WD, Rozing J. Bone marrow does not contribute substantially to endothelial-cell replacement in transplant arteriosclerosis. Nat Med. 2002;8:194–195
  34. Hu Y, Davison F, Ludewig B, Erdel M, Mayr M, Url M, et al. Smooth muscle cells in transplant atherosclerotic lesions are originated from recipients, but not bone marrow progenitor cells. Circulation. 2002;106:1834–1839
  35. Fukuda D, Sata M, Tanaka K, Nagai R. Potent inhibitory effect of sirolimus on circulating vascular progenitor cells. Circulation. 2005;111:926–931
  36. Simper D, Stalboerger PG, Panetta CJ, Wang S, Caplice NM. Smooth muscle progenitor cells in human blood. Circulation. 2002;106:1199–1204
  37. Bocan TM. Animal models of atherosclerosis and interpretation of drug intervention studies. Curr Pharm Des. 1998;4:37–52
  38. Torikai K, Ichikawa H, Hirakawa K, Matsumiya G, Kuratani T, Iwai S, et al. A self-renewing, tissue-engineered vascular graft for arterial reconstruction. J Thorac Cardiovasc Surg. 2008;136:37–45e1

 This study was supported in part by the Program for Promotion of Basic and Applied Researches for Innovations in Bio-oriented Industry and by grants from the Ministry of Education, Culture, Sports, Science and Technology of Japan (Knowledge Cluster and New Research Area).

 Competition of interest: none.

 The editors and reviewers of this article have no relevant financial relationships to disclose per the JVS policy that requires reviewers to decline review of any manuscript for which they may have a competition of interest.

PII: S0741-5214(09)01835-7

doi: 10.1016/j.jvs.2009.09.005

Journal of Vascular Surgery
Volume 51, Issue 1 , Pages 155-164 , January 2010