Journal of Vascular Surgery
Volume 50, Issue 6 , Pages 1444-1451 , December 2009

DNA-array of gene variants in venous leg ulcers: Detection of prognostic indicators

  • Donato Gemmati, PhD

      Affiliations

    • Haemostasis & Thrombosis Center, University of Ferrara, Ferrara, Italy
    • Vascular Disease Center, University of Ferrara, Ferrara, Italy
    • Corresponding Author InformationReprint requests: Donato Gemmati, PhD, Haemostasis & Thrombosis Center, Biomedical Sciences & Advanced Therapies, Unit of Haematology, University of Ferrara, C. So Giovecca 203, I-44100 Ferrara, Italy
    • ,
  • Federica Federici, PhD

      Affiliations

    • Haemostasis & Thrombosis Center, University of Ferrara, Ferrara, Italy
    • Vascular Disease Center, University of Ferrara, Ferrara, Italy
    • ,
  • Linda Catozzi, PhD

      Affiliations

    • Haemostasis & Thrombosis Center, University of Ferrara, Ferrara, Italy
    • Vascular Disease Center, University of Ferrara, Ferrara, Italy
    • ,
  • Sergio Gianesini, MD

      Affiliations

    • Vascular Disease Center, University of Ferrara, Ferrara, Italy
    • ,
  • Giovanna Tacconi, MD

      Affiliations

    • Vascular Disease Center, University of Ferrara, Ferrara, Italy
    • ,
  • Gian L. Scapoli, MD

      Affiliations

    • Haemostasis & Thrombosis Center, University of Ferrara, Ferrara, Italy
    • Vascular Disease Center, University of Ferrara, Ferrara, Italy
    • ,
  • Paolo Zamboni, MD

      Affiliations

    • Vascular Disease Center, University of Ferrara, Ferrara, Italy

Received 6 February 2009 ,Accepted 25 July 2009.

  • Image Result

    Whole cohort of subjects investigated. C3-C6 according to CEAP international classification of CVD. CVD, Chronic venous disease; VLU, venous leg ulcer.

    Whole cohort of subjects investigated. C3-C6 according to CEAP international classification of CVD. CVD, Chronic venous disease; VLU, venous leg ulcer.

  • Image Result

    Relationships between MMP12 −82AG polymorphism and venous ulcer size. Mean and SD values are reported. The P value is obtained by t test.

    Relationships between MMP12 −82AG polymorphism and venous ulcer size. Mean and SD values are reported. The P value is obtained by t test.

  • Image Result

    Relationships between FXIII V34L polymorphism and venous ulcer size. Mean and SD values are reported. The P value is obtained by test for trend.

    Relationships between FXIII V34L polymorphism and venous ulcer size. Mean and SD values are reported. The P value is obtained by test for trend.

 This study was supported in part by funds from MIUR (the Italian Ministry for University Instruction and Research) and thanks to a grant from Fondazione Cassa di Risparmio - Cento, Italy.

 Competition of interest: none.

 The editors and reviewers of this article have no relevant financial relationships to disclose per the JVS policy that requires reviewers to decline review of any manuscript for which they may have a competition of interest.

PII: S0741-5214(09)01576-6

doi: 10.1016/j.jvs.2009.07.103

Journal of Vascular Surgery
Volume 50, Issue 6 , Pages 1444-1451 , December 2009

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