Journal of Vascular Surgery
Volume 50, Issue 4 , Pages 769-775 , October 2009

Validation of the PIII CLI risk score for the prediction of amputation-free survival in patients undergoing infrainguinal autogenous vein bypass for critical limb ischemia

Presented at the 2009 Vascular Annual Meeting, Denver, Colo, June 11-14, 2009.

  • Andres Schanzer, MD

      Affiliations

    • University of Massachusetts Medical School, Worcester, Mass
    • Corresponding Author InformationReprint requests: Andres Schanzer, MD, Division of Vascular and Endovascular Surgery, University of Massachusetts Memorial Medical Center, 55 Lake Ave North, Worcester, MA 01655
  • ,
  • Philip P. Goodney, MD, MS

      Affiliations

    • Dartmouth-Hitchcock Medical Center, Lebanon, NH
  • ,
  • Youfu Li, MD, MPH

      Affiliations

    • University of Massachusetts Medical School, Worcester, Mass
  • ,
  • Mohammad Eslami, MD

      Affiliations

    • University of Massachusetts Medical School, Worcester, Mass
  • ,
  • Jack Cronenwett, MD

      Affiliations

    • Dartmouth-Hitchcock Medical Center, Lebanon, NH
  • ,
  • Louis Messina, MD

      Affiliations

    • University of Massachusetts Medical School, Worcester, Mass
  • ,
  • Michael S. Conte, MD

      Affiliations

    • University of California San Francisco, San Francisco, Calif
  • ,
  • Vascular Study Group of Northern New England

Received 4 May 2009 ,Accepted 28 May 2009.

  • Image Result

    Score card. PIII, PREVENT III; HCT, hematocrit; CAD, coronary artery disease.

    Score card. PIII, PREVENT III; HCT, hematocrit; CAD, coronary artery disease.

  • Image Result

    Kaplan-Meier curves demonstrating amputation-free (AF) survival stratified according to each patient's calculated risk score (Vascular Study Group of Northern New England [VSGNNE] cohort).

    Kaplan-Meier curves demonstrating amputation-free (AF) survival stratified according to each patient's calculated risk score (Vascular Study Group of Northern New England [VSGNNE] cohort).

  • Image Result

    Validation of the PREVENT III (PIII) critical limb ischemia (CLI) risk score in 4 different datasets (3286 patients)—PIII derivation set, PIII validation set, retrospective validation set, prospective

    Validation of the PREVENT III (PIII) critical limb ischemia (CLI) risk score in 4 different datasets (3286 patients)—PIII derivation set, PIII validation set, retrospective validation set, prospective Vascular Study Group of Northern New England (VSGNNE) validation set. AF, Amputation-free.

  • Image Result
    Risk category breakdown by predictor (Vascular Study Group of Northern New England [VSGNNE] cohort). CAD, Coronary artery disease.

    Risk category breakdown by predictor (Vascular Study Group of Northern New England [VSGNNE] cohort). CAD, Coronary artery disease.

  • Image Result
    PREVENT III (PIII) critical limb ischemia (CLI) risk score was an effective tool for discriminating three significant strata of risk when tested on the following endpoints: perioperative major adverse

    PREVENT III (PIII) critical limb ischemia (CLI) risk score was an effective tool for discriminating three significant strata of risk when tested on the following endpoints: perioperative major adverse cardiac event (MACE) (a), perioperative and 1-year mortality (b), and 1-year ability to ambulate (c).

 Competition of interest: none.

PII: S0741-5214(09)01191-4

doi: 10.1016/j.jvs.2009.05.055

Journal of Vascular Surgery
Volume 50, Issue 4 , Pages 769-775 , October 2009