Journal of Vascular Surgery
Volume 50, Issue 4 , Pages 813-819.e1 , October 2009

Restenosis after renal artery angioplasty and stenting: Incidence and risk factors

Presented at the Thirty-third Annual Meeting of the Southern Association of Vascular Surgery, Tucson, Ariz, Jan 14, 2009.

  • Matthew A. Corriere, MD, MS

      Affiliations

    • Department of Vascular and Endovascular Surgery, Wake Forest University School of Medicine, Winston-Salem, NC
    • ,
  • Matthew S. Edwards, MD, MS

      Affiliations

    • Department of Vascular and Endovascular Surgery, Wake Forest University School of Medicine, Winston-Salem, NC
    • ,
  • Jeffrey D. Pearce, MD

      Affiliations

    • Department of Vascular and Endovascular Surgery, Wake Forest University School of Medicine, Winston-Salem, NC
    • ,
  • Jeanette S. Andrews, MS

      Affiliations

    • Department of Biostatistical Sciences, Wake Forest University School of Medicine, Winston-Salem, NC
    • ,
  • Randolph L. Geary, MD

      Affiliations

    • Department of Vascular and Endovascular Surgery, Wake Forest University School of Medicine, Winston-Salem, NC
    • ,
  • Kimberley J. Hansen, MD

      Affiliations

    • Department of Vascular and Endovascular Surgery, Wake Forest University School of Medicine, Winston-Salem, NC
    • Corresponding Author InformationReprint requests: Kimberley J. Hansen, MD, Department of Vascular and Endovascular Surgery, Medical Center Blvd, Winston-Salem, NC 27157-1095

Received 10 January 2009 ,Accepted 12 May 2009.

References 

  1. Edwards MS, Craven TE, Burke GL, Dean RH, Hansen KJ. Renovascular disease and the risk of adverse coronary events in the elderly: a prospective, population-based study. Arch Intern Med. 2005;165:207–213
  2. Leertouwer TC, Gussenhoven EJ, Bosch JL, van Jaarsveld BC, van Dijk LC, Deinum J, et al. Stent placement for renal arterial stenosis: where do we stand? A meta-analysis. Radiology. 2000;216:78–85
  3. Baumgartner I, von Aesch K, Do DD, Triller J, Birrer M, Mahler F. Stent placement in ostial and nonostial atherosclerotic renal arterial stenoses: a prospective follow-up study. Radiology. 2000;216:498–505
  4. Dorros G, Jaff M, Jain A, Dufek C, Mathiak L. Follow-up of primary Palmaz-Schatz stent placement for atherosclerotic renal artery stenosis. Am J Cardiol. 1995;75:1051–1055
  5. Lederman RJ, Mendelsohn FO, Santos R, Phillips HR, Stack RS, Crowley JJ. Primary renal artery stenting: characteristics and outcomes after 363 procedures. Am Heart J. 2001;142:314–323
  6. Nolan BW, Schermerhorn ML, Powell RJ, Rowell E, Fillinger MF, Rzucidlo EM, et al. Restenosis in gold-coated renal artery stents. J Vasc Surg. 2005;42:40–46
  7. Nolan BW, Schermerhorn ML, Rowell E, Powell RJ, Fillinger MF, Rzucidlo EM, et al. Outcomes of renal artery angioplasty and stenting using low-profile systems. J Vasc Surg. 2005;41:46–52
  8. Tullis MJ, Zierler RE, Glickerman DJ, Bergelin RO, Cantwell-Gab K, Strandness DE. Results of percutaneous transluminal angioplasty for atherosclerotic renal artery stenosis: a follow-up study with duplex ultrasonography. J Vasc Surg. 1997;25:46–54
  9. Bates MC, Rashid M, Campbell JE, Stone PA, Broce M, Lavigne PS. Factors influencing the need for target vessel revascularization after renal artery stenting. J Endovasc Ther. 2006;13:569–577
  10. Vignali C, Bargellini I, Lazzereschi M, Cioni R, Petruzzi P, Caramella D, et al. Predictive factors of in-stent restenosis in renal artery stenting: a retrospective analysis. Cardiovasc Intervent Radiol. 2005;28:296–302
  11. Kane GC, Hambly N, Textor SC, Stanson AW, Garovic VD. Restenosis following percutaneous renal artery revascularization. Nephron Clin Pract. 2007;107:c63–c69
  12. Shammas NW, Kapalis MJ, Dippel EJ, Jerin MJ, Lemke JH, Patel P, et al. Clinical and angiographic predictors of restenosis following renal artery stenting. J Invasive Cardiol. 2004;16:10–13
  13. Edwards MS, Craven BL, Stafford J, Craven TE, Sauve KJ, Ayerdi J, et al. Distal embolic protection during renal artery angioplasty and stenting. J Vasc Surg. 2006;44:128–135
  14. Corriere MA, Pearce JD, Edwards MS, Stafford J, Hansen KJ. Endovascular management of atherosclerotic renal artery stenosis: early results following primary intervention. J Vasc Surg. 2008;48:580–587
  15. Levey AS, Bosch JP, Lewis JB, Greene T, Rogers N, Roth D. A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation (Modification of Diet in Renal Disease Study Group). Ann Intern Med. 1999;130:461–470
  16. Radermacher J, Chavan A, Bleck J, Vitzthum A, Stoess B, Gebel MJ, et al. Use of Doppler ultrasonography to predict the outcome of therapy for renal-artery stenosis. N Engl J Med. 2001;344:410–417
  17. Hansen KJ, Tribble RW, Reavis SW, Canzanello VJ, Craven TE, Plonk GW, et al. Renal duplex sonography: evaluation of clinical utility. J Vasc Surg. 1990;12:227–236
  18. Bakker J, Beutler JJ, Elgersma OE, de Lange EE, de Kort GA, Beek FJ. Duplex ultrasonography in assessing restenosis of renal artery stents. Cardiovasc Intervent Radiol. 1999;22:475–480
  19. Napoli V, Pinto S, Bargellini I, Vignali C, Cioni R, Petruzzi P, et al. Duplex ultrasonographic study of the renal arteries before and after renal artery stenting. Eur Radiol. 2002;12:796–803
  20. Parenti GC, Palmarini D, Bilzoni M, Campioni P, Mannella P, Ginevra A. Role of color-Doppler sonography in the follow-up of renal artery stenting. Radiol Med (Torino). 2008;113:242–248
  21. Motew SJ, Cherr GS, Craven TE, Travis JA, Wong JM, Reavis SW, et al. Renal duplex sonography: main renal artery versus hilar analysis. J Vasc Surg. 2000;32:462–469
  22. Kastrati A, Schomig A, Elezi S, Schuhlen H, Dirschinger J, Hadamitzky M, et al. Predictive factors of restenosis after coronary stent placement. J Am Coll Cardiol. 1997;30:1428–1436
  23. Davignon J. Beneficial cardiovascular pleiotropic effects of statins. Circulation. 2004;109(23 suppl 1):III39–III43
  24. Calabro P, Yeh ET. The pleiotropic effects of statins. Curr Opin Cardiol. 2005;20:541–546
  25. Cheung CM, Patel A, Shaheen N, Cain S, Eddington H, Hegarty J, et al. The effects of statins on the progression of atherosclerotic renovascular disease. Nephron Clin Pract. 2007;107:c35–c42
  26. Erl W, Hristov M, Neureuter M, Yan ZQ, Hansson GK, Weber PC. HMG-CoA reductase inhibitors induce apoptosis in neointima-derived vascular smooth muscle cells. Atherosclerosis. 2003;169:251–258
  27. Erl W. Atorvastatin-induced downregulation of survivin and vascular smooth muscle cell apoptosis: a causal relationship in restenosis?. Cardiovasc Drugs Ther. 2007;21:141–144
  28. Crisby M, Nordin-Fredriksson G, Shah PK, Yano J, Zhu J, Nilsson J. Pravastatin treatment increases collagen content and decreases lipid content, inflammation, metalloproteinases, and cell death in human carotid plaques: implications for plaque stabilization. Circulation. 2001;103:926–933
  29. Heeneman S, Sluimer JC, Daemen MJ. Angiotensin-converting enzyme and vascular remodeling. Circ Res. 2007;101:441–454

 Dr Edwards is supported by the American Vascular Association and Lifeline Foundation Research Career Development Award. Grant support was also provided by The National Heart, Lung, and Blood Institute of the National Institutes of Health to Dr Edwards (Grant 1K23HL083981-01), Dr Geary (Grant R01 HL57557), and Dr Hansen (Grant 5K12HL083763-02).

 Competition of interest: none.

 Additional material for this article may be found online at www.jvascsurg.org.

PII: S0741-5214(09)01031-3

doi: 10.1016/j.jvs.2009.05.019

Journal of Vascular Surgery
Volume 50, Issue 4 , Pages 813-819.e1 , October 2009

Article Tools

* Image Usage & Resolution