Carotid angioplasty and stenting in anatomically high-risk patients: Safe and durable except for radiation-induced stenosis

Kaplan-Meier stroke-free survival curves for the medical high-risk (MED) cohort (black line) and anatomic high-risk (ANAT) cohort (gray line) were similar at 1 year (MED, 93.6%; ANAT, 98.9%) and 2 years (MED, 93.6%; ANAT, 98.9%; P = .118). Abbreviated life-table data are included along the horizontal axis.

Kaplan-Meier overall survival curves were better for the anatomic high-risk (ANAT) cohort (gray line) than for the medical high-risk (MED) cohort (black line) at 1 year (ANAT, 89.5%; MED, 85.1%) and 2 years (ANAT, 84.6%; MED, 70.1%; P = .026). Abbreviated life-table data are included along the horizontal axis.

Kaplan-Meier curves show restenosis-free survival for the medical high-risk (MED) cohort (black line) and anatomic high-risk (ANAT) cohort (gray line) were similar at 1 year (MED, 91.9%; ANAT, 95.2%) and 2 years (MED, 91.9%; ANAT, 91.0%; P = .98). Abbreviated life-table data are included along the horizontal axis.

Kaplan-Meier curves show restenosis-free survival was significantly better for the patients in the anatomic high risk cohort without a history of radiation (non-RAD, gray line) than for those patients in the anatomic high risk cohort with a history of radiation (RAD, black line) at 1 year (non-RAD, 98.3%; RAD, 83.1%) and 2 years (non-RAD, 95.9%; RAD, 72.7%; P = .017). Restenosis-free survival for patients without a history of radiation at 3 years was 92.8%. The standard error of the mean was >10% past 2 years (dotted line). Abbreviated life-table data are included along the horizontal axis.