Journal of Vascular Surgery
Volume 49, Issue 2 , Pages 302-306, February 2009

Spinal cord ischemia after TEVAR in patients with abdominal aortic aneurysms

Presented at the Thirty-second Annual Meeting of the Southern Association for Vascular Surgery, Naples, Fla, Jan 16-19, 2008.

  • Daniel J. Martin, MD

      Affiliations

    • Division of Vascular Surgery and Endovascular Therapy, University of Florida, Gainesville, Fla
  • ,
  • Tomas D. Martin, MD

      Affiliations

    • Division of Thoracic and Cardiovascular Surgery, University of Florida, Gainesville, Fla
  • ,
  • Philip J. Hess, MD

      Affiliations

    • Division of Thoracic and Cardiovascular Surgery, University of Florida, Gainesville, Fla
  • ,
  • Michael J. Daniels, ScD

      Affiliations

    • Department of Epidemiology and Biostatistics, University of Florida, Gainesville, Fla
  • ,
  • Robert J. Feezor, MD

      Affiliations

    • Division of Vascular Surgery and Endovascular Therapy, University of Florida, Gainesville, Fla
  • ,
  • W. Anthony Lee, MD

      Affiliations

    • Division of Vascular Surgery and Endovascular Therapy, University of Florida, Gainesville, Fla
    • Corresponding Author InformationReprint requests: W. Anthony Lee, MD, Division of Vascular Surgery and Endovascular Therapy, 1600 SW Archer Road, Suite NG-45, Post Office Box 100286, Gainesville, FL 32610-0286

Received 25 May 2008; accepted 29 August 2008. published online 25 November 2008.

Objective

To examine the incidence of and the anatomic factors that may contribute to spinal cord ischemia (SCI) in patients with a history of abdominal aortic aneurysms (AAA) after thoracic endovascular aortic repair (TEVAR).

Methods

The medical records, computed tomography (CT) angiograms, and a prospectively maintained clinical database of all TEVAR patients at a single institution between 2000 and 2007 were reviewed. Select preoperative demographics, thoracoabdominal aortoiliac anatomy, intraoperative procedural variables, and postoperative outcomes were examined. Univariate and multivariate analyses were performed and odds ratio estimates were reported with 95% confidence intervals.

Results

Of the 261 patients who underwent TEVAR, 27 developed SCI (10%). Thirteen (48%) of these 27 patients were completely reversed with spinal drainage, and 14 (52%) were permanent. Patients with SCI tended to be older (P = .006), male (P = .049), and required more emergent procedures (P = .051) performed under general anesthesia (P = .004). Interestingly, while prior AAA repair (50/261, 19%) alone was not associated with SCI (P = .44), a history of either repaired or unrepaired AAA (101/261, 39%) was a predictor of SCI on multivariate analysis (odds ratio [OR] = 4.35 [1.43, 14.3], P = .10), independent of thoracic aortic coverage (P = .001) and lumbar artery patency (P = .008), both of which were also associated with SCI.

Conclusion

Although the causes of SCI after TEVAR are multifactorial, abdominal aortic anatomy appears to be associated with development of this complication. Patients with either prior AAA repair or those with unrepaired AAA appear to be at increased risk for SCI.

 

 Competition of interest: none.

 CME article

PII: S0741-5214(08)01633-9

doi:10.1016/j.jvs.2008.08.119

Journal of Vascular Surgery
Volume 49, Issue 2 , Pages 302-306, February 2009