Journal of Vascular Surgery
Volume 49, Issue 1 , Pages 127-132 , January 2009

Peripheral arterial disease affects kinematics during walking

  • Rolando Celis, MD

      Affiliations

    • University of Nebraska Medical Center, Omaha, Neb
    • Veterans Affairs Medical Center of Nebraska, Omaha, Neb
    • ,
  • Iraklis I. Pipinos, MD

      Affiliations

    • University of Nebraska Medical Center, Omaha, Neb
    • Veterans Affairs Medical Center of Nebraska, Omaha, Neb
    • ,
  • Melissa M. Scott-Pandorf, MS

      Affiliations

    • University of Nebraska at Omaha, Omaha, Neb
    • ,
  • Sara A. Myers, MS

      Affiliations

    • University of Nebraska at Omaha, Omaha, Neb
    • ,
  • Nicholas Stergiou, PhD

      Affiliations

    • University of Nebraska at Omaha, Omaha, Neb
    • ,
  • Jason M. Johanning, MD

      Affiliations

    • University of Nebraska Medical Center, Omaha, Neb
    • Veterans Affairs Medical Center of Nebraska, Omaha, Neb
    • Corresponding Author InformationReprint requests: Jason M. Johanning, MD, University of Nebraska Medical Center, Section of Vascular Surgery, Omaha, NE 68198-3280

Received 26 April 2008 ,Accepted 9 August 2008.

References 

  1. Hirsch AT, Criqui MH, Treat-Jacobson D, Regensteiner JG, Creager MA, Olin JW, et al. Peripheral arterial disease detection, awareness, and treatment in primary care. JAMA. 2001;286:1317–1324
  2. McDermott MM, Kerwin DR, Liu K, Martin GJ, O'Brien E, Kaplan H, et al. Prevalence and significance of unrecognized lower extremity peripheral arterial disease in general medicine practice. J Gen Intern Med. 2001;16:384–390
  3. Becker GJ, McClenny TE, Kovacs ME, Raabe RD, Katzen BT. The importance of increasing public and physiscian awareness of peripheral arterial disease. J Vasc Interv Radiol. 2002;13:7–11
  4. Nehler M, McDermott M, Treat-Jacobson D, Chetter I, Regensteiner J. Functional outcomes and quality of life in peripheral arterial disease: Current status. Vasc Med. 2003;8:115–126
  5. Sieminski DJ, Gardner AW. The relationship between daily physical activity and the severity of peripheral arterial occlusive disease. Vasc Med. 1997;2:286–291
  6. Scott-Okafor HR, Silver K, Parker J, Gardner AW. Lower extremity strength deficits in peripheral arterial occlusive disease patents with intermittent claudication. Angiology. 2001;52:7–14
  7. Regensteiner JG, Steiner JF, Panzer RJ, Hiatt WR. Evaluation of walking impairment by questionnaire in patients with peripheral artery disease. J Vasc Med Biol. 1990;2:142–152
  8. Feinglass J, McCarthy WJ, Slavensky R, Manheim LM, Martin GJ. Effect of lower extremity blood pressure on physical functioning in patients who have intermittent claudication (The Chicago Claudication Outcomes Research Group). J Vasc Surg. 1996;24:503–511
  9. Gardner AW, Montgomery PS. Impaired balance and higher prevalence of falls in subjects with intermittent claudication. J Gerontol A Biol Sci Med Sci. 2001;56:454–458
  10. Scherer SA, Bainbridge JS, Hiatt WR, Regensteiner JG. Gait characteristics of patients with claudication. Arch Phys Med Rehabil. 1998;79:529–531
  11. McCully K, Leiper C, Sanders T, Griffin E. The effects of peripheral vascular disease on gait. J Gerontol. 1999;54A:291–294
  12. Kay RM, Dennis S, Rethlefsen S, Reynolds RA, Skaggs DL, Tolo VT. The effect of preoperative gait analysis on orthopaedic decision making. Clin Orthop Relat Res. 2000;217–222
  13. Ounpuu S, Gage JR, Davis RB. Three-dimensional lower extremity joint kinetics in normal pediatric gait. J Pediatr Orthop. 1991;11:341–349
  14. McClelland JA, Webster KE, Feller JA. Gait analysis of patients following total knee replacement: a systematic review. Knee. 2007;14:253–263
  15. Lee EH, Goh JC, Bose K. Value of gait analysis in the assessment of surgery in cerebral palsy. Arch Phys Med Rehabil. 1992;73:642–646
  16. Gardner AW, Montgomery PS. The relationship between history of falling and physical function in subjects with peripheral arterial disease. Vasc Med. 2001;6:223–227
  17. Crowther RG, Spinks WL, Leicht AS, Quigley F, Golledge J. Relationship between temporal-spatial gait parameters, gait kinematics, walking performance, exercise capacity, and physical activity level in peripheral arterial disease. J Vasc Surg. 2007;45:1172–1178
  18. Scott-Pandorf MM, Stergiou N, Johanning JM, Robinson L, Lynch TG, Pipinos II. Peripheral arterial disease affects ground reaction forces during walking. J Vasc Surg. 2007;46:491–499
  19. Rose G. The diagnosis of ischaemic heart pain and intermittent claudication if field surveys. Bull World Health Organ. 1962;27:645–658
  20. In:  Vaughan CL,  Davis BL,  O'Connor J editor. Dynamics of human gait. 2nd edition. Cape Town, South Africa: Kiboho; 1999;p. 90–106
  21. Nigg BM, Cole G, Nachbauer W. Effects of arch height of the foot on angular motion of the lower extremities in running. J Biomech. 1993;26:909–916
  22. Jackson KM. Fitting of mathematical functions to biomechanical data (IEEE Trans). Biomed Eng. 1979;26:122–124
  23. Woltring HJ. On optimal smoothing and derivative estimation from noisy displacement data in biomechanics. Hum Mov Sci. 1985;4:229–245
  24. Giakas G. Power spectrum analysis and filtering. In:  Stergiou N editors. Innovative analyses in human movement. Champaign IL: Human Kinetics Inc; 2004;p. 223–250
  25. Rutherford RB, Baker JD, Ernst C, Johnston KW, Porter JM, Ahn S, et al. Recommended standards for reports dealing with lower extremity ischemia: revised version. J Vasc Surg. 1997;26:517–538
  26. Koopman JP, de Vries AC, de Weerd AW. Neuromuscular disorders in patients with intermittent claudication. Eur J Surg. 1996;162:443–446
  27. Laghi Pasini F, Pastorelli M, Beermann U, de Candia S, Gallo S, Blardi P, et al. Peripheral neuropathy associated with ischemic vascular disease of the lower limbs. Angiology. 1996;47:569–577
  28. Pipinos II, Judge AR, Selsby JT, Zhu Z, Swanson SA, Nella AA, et al. The myopathy of peripheral arterial occlusive disease: part 1 (Functional and histomorphological changes and evidence for mitochondrial dysfunction). Vasc Endovascular Surg. 2007;41:481–489
  29. Womack CJ, Sieminski DJ, Katzel LI, Yataco A, Gardner AW. Improved walking economy in patients with peripheral arterial occlusive disease. Med Sci Sports Exerc. 1997;29:1286–1290
  30. Kuo AD. The six determinants of gait and the inverted pendulum analogy: A dynamic walking perspective. Hum Mov Sci. 2007;26:617–656
  31. Brass EP, Hiatt WR. Acquired skeletal muscle metabolic myopathy in atherosclerotic peripheral arterial disease. Vasc Med. 2000;5:55–59
  32. Marbini A, Gemignani F, Scoditti U, Rustichelli P, Bragaglia MM, Govoni E. Abnormal muscle mitochondria in ischemic claudication. Acta Neurol Belg. 1986;86:304–310
  33. Pipinos II, Judge AR, Zhu Z, Selsby JT, Swanson SA, Johanning JM, et al. Mitochondrial defects and oxidative damage in patients with peripheral arterial disease. Free Radic Biol Med. 2006;41:262–269
  34. Pipinos II, Shepard AD, Anagnostopoulos PV, Katsamouris A, Boska MD. Phosphorus 31 nuclear magnetic resonance spectroscopy suggests a mitochondrial defect in claudicating skeletal muscle. J Vasc Surg. 2000;31:944–952
  35. Kemp GJ. Mitochondrial dysfunction in chronic ischemia and peripheral vascular disease. Mitochondrion. 2004;4:629–640
  36. Makris KI, Nella AA, Zhu Z, Swanson SA, Casale GP, Gutti TL, et al. Mitochondriopathy of peripheral arterial disease. Vascular. 2007;15:336–343
  37. Pipinos II, Sharov VG, Shepard AD, Anagnostopoulos PV, Katsamouris A, Todor A, et al. Abnormal mitochondrial respiration in skeletal muscle in patients with peripheral arterial disease. J Vasc Surg. 2003;38:827–832
  38. Judge JO, Ounpuu S, Davis RB. Effects of age on the biomechanics and physiology of gait. Clin Geriatr Med. 1996;12:659–678
  39. Areblad M, Nigg BM, Ekstrand J, Olsson KO, Ekström H. Three-dimensional measurement of rearfoot motion during running. J Biomech. 1990;23:933–940
  40. In:  Allard P,  Capozzo A,  Lundberg A,  Vaughan C editor. Three-dimensional analysis of human locomotion. West Sussex, United Kingdom: John Wiley and Sons, Ltd; 1997;

 Grant funding for the current study was provided by the American Geriatrics Society's Hartford Foundation Dennis W. Jahnigen Award, the Nebraska Research Initiative and the University of Community on Research and Creative Activity at University of Nebraska at Omaha.

 Competition of interest: none.

PII: S0741-5214(08)01363-3

doi: 10.1016/j.jvs.2008.08.013

Journal of Vascular Surgery
Volume 49, Issue 1 , Pages 127-132 , January 2009

Article Tools

* Image Usage & Resolution