Journal of Vascular Surgery
Volume 48, Issue 6 , Pages 1509-1513 , December 2008

Integrity of venoarteriolar reflex determines level of microvascular skin flow enhancement with intermittent pneumatic compression

  • Marc Husmann, MD

      Affiliations

    • Division of Angiology, University Hospital Bern, Bern, Switzerland
    • Division of Angiology, University Hospital Zurich, Zurich, Switzerland
    • Corresponding Author InformationReprint requests: Marc Husmann, MD, Angiology Division, University Hospital Zurich, Ramistrasse 100, 8091 Zurich, Switzerland
  • ,
  • Torsten Willenberg, MD

      Affiliations

    • Division of Angiology, University Hospital Bern, Bern, Switzerland
  • ,
  • Hak Hong Keo, MD

      Affiliations

    • Division of Angiology, University Hospital Bern, Bern, Switzerland
  • ,
  • Silviana Spring, MD

      Affiliations

    • Division of Angiology, University Hospital Zurich, Zurich, Switzerland
  • ,
  • Evi Kalodiki, MD, PhD

      Affiliations

    • Imperial College School of Medicine, Zurich, Switzerland
  • ,
  • Kostas T. Delis, MSc, MD, MS, PhD

      Affiliations

    • Department of Vascular Surgery, Athens Medical Center, Marousi, Athens, Greece

Received 1 May 2008 ,Accepted 10 July 2008.

  • Image Result

    Pedal skin blood flow in recumbent and dependent position in controls and patients with peripheral arterial disease.

    Pedal skin blood flow in recumbent and dependent position in controls and patients with peripheral arterial disease.

  • Image Result

    Veno-arteriolar response in controls and patients with peripheral arterial disease.

    Veno-arteriolar response in controls and patients with peripheral arterial disease.

  • Image Result

    Percentage skin blood flow increase on intermittent pneumatic compression applied to the foot, the calf or both in healthy controls and claudicants.

    Percentage skin blood flow increase on intermittent pneumatic compression applied to the foot, the calf or both in healthy controls and claudicants.

  • Image Result

    Spearman correlations between veno-arteriolar response and skin blood flux augmentation (percentage increase) with intermittent pneumatic compression applied to (a) the calf (r = 0.58, P = .002), (b)

    Spearman correlations between veno-arteriolar response and skin blood flux augmentation (percentage increase) with intermittent pneumatic compression applied to (a) the calf (r = 0.58, P = .002), (b) the foot (r = 0.65, P < .0001), or (c) foot and calf (r = 0.64, P = .0002), both in healthy controls and claudicants.

 Supported by the Swiss Heart Foundation and the Roche Science Foundation.

 Competition of interest: none.

PII: S0741-5214(08)01173-7

doi: 10.1016/j.jvs.2008.07.016

Journal of Vascular Surgery
Volume 48, Issue 6 , Pages 1509-1513 , December 2008