Journal of Vascular Surgery
Volume 48, Issue 6 , Pages 1451-1457.e3 , December 2008

The management of severe aortoiliac occlusive disease: Endovascular therapy rivals open reconstruction

Presented in part at the 2007 Annual Vascular Meeting, Baltimore, Md, Jun 7-10, 2007.

  • Vikram S. Kashyap, MD

      Affiliations

    • Department of Vascular Surgery, The Cleveland Clinic, Cleveland, Ohio
    • Corresponding Author InformationReprint requests: Vikram S. Kashyap, MD, Cleveland Clinic Foundation, Department of Vascular Surgery, S40, 9500 Euclid Ave, Cleveland, OH 44195
  • ,
  • Mircea L. Pavkov, MD

      Affiliations

    • Department of Vascular Surgery, The Cleveland Clinic, Cleveland, Ohio
  • ,
  • James F. Bena, MS

      Affiliations

    • Department of Quantitative Health Sciences, The Cleveland Clinic, Cleveland, Ohio
  • ,
  • Timur P. Sarac, MD

      Affiliations

    • Department of Vascular Surgery, The Cleveland Clinic, Cleveland, Ohio
  • ,
  • Patrick J. O'Hara, MD

      Affiliations

    • Department of Vascular Surgery, The Cleveland Clinic, Cleveland, Ohio
  • ,
  • Sean P. Lyden, MD

      Affiliations

    • Department of Vascular Surgery, The Cleveland Clinic, Cleveland, Ohio
  • ,
  • Daniel G. Clair, MD

      Affiliations

    • Department of Vascular Surgery, The Cleveland Clinic, Cleveland, Ohio

Received 14 May 2008 ,Revised 9 July 2008

  • Image Result

    A, Transbrachial aortography documents an aortic occlusion in a 68-year old woman with rest pain. Late images document the presence of distal iliac arteries reconstituted via collaterals (not shown) B

    A, Transbrachial aortography documents an aortic occlusion in a 68-year old woman with rest pain. Late images document the presence of distal iliac arteries reconstituted via collaterals (not shown) B, Femoral access is obtained with ultrasound guidance and endovascular recanalization is performed using a hydrophilic guidewire and catheter. Primary stenting using self-expanding nitinol stents with postdeployment balloon angioplasty restores normal pulsatile perfusion to both lower extremities. Bottom panels, Inaudible Doppler signals preoperatively to ankle-brachial indices of 1.0 bilaterally, transmetatarsal and digital waveforms are shown.

  • Image Result
    Distribution of patients undergoing aortobifemoral (ABF; striped bars) bypass and recanalization, percutaneous transluminal angioplasty, and stenting (R/PTAS, dotted bars) classified by TransAtlantic

    Distribution of patients undergoing aortobifemoral (ABF; striped bars) bypass and recanalization, percutaneous transluminal angioplasty, and stenting (R/PTAS, dotted bars) classified by TransAtlantic InterSociety Concensus (TASC) criteria. Both groups had similar distribution of extensive aortoiliac occlusive disease treated by either open (ABFB) or endovascular (R/PTAS) techniques.

  • Image Result
    A, Kaplan-Meier curve estimates for (A) primary patency, (B) secondary patency, and (C) limb salvage in patients undergoing aortobifemoral (ABF; solid line) bypass vs recanalization, percutaneous tran

    A, Kaplan-Meier curve estimates for (A) primary patency, (B) secondary patency, and (C) limb salvage in patients undergoing aortobifemoral (ABF; solid line) bypass vs recanalization, percutaneous transluminal angioplasty, and stenting (R/PTAS, dashed line) over 36 months (standard error <10%). A, Primary patency for ABF bypass was 93%, which was significantly higher than 74% for patients undergoing R/PTAS (P = .002). B, Secondary patency was 97% for patients undergoing ABF bypass vs 95% for R/PTAS. No significant difference was found between groups (P = .3). C, Limb salvage rates were 98% for both groups (P = .97).

  • Image Result
    Survival for patients undergoing aortobifemoral (ABF; solid line) bypass vs recanalization, percutaneous transluminal angioplasty, and stenting (R/PTAS, dashed line) was equivalent at 36 months (80%)

    Survival for patients undergoing aortobifemoral (ABF; solid line) bypass vs recanalization, percutaneous transluminal angioplasty, and stenting (R/PTAS, dashed line) was equivalent at 36 months (80%) by Kaplan-Meier analyses. Standard error <10%.

 Competition of interest: none.

 Additional material for this article may be found online at www.jvascsurg.org.

PII: S0741-5214(08)01139-7

doi: 10.1016/j.jvs.2008.07.004

Journal of Vascular Surgery
Volume 48, Issue 6 , Pages 1451-1457.e3 , December 2008