Journal of Vascular Surgery
Volume 47, Issue 3 , Pages 599-607 , March 2008

Role of redox signaling and poly (adenosine diphosphate-ribose) polymerase activation in vascular smooth muscle cell growth inhibition by nitric oxide and peroxynitrite

  • James Huang, MD

      Affiliations

    • Department of Surgery, San Francisco Veteran’s Affairs Medical Center and Pacific Vascular Research Laboratories, Division of Vascular Surgery, University of California, San Francisco, Calif
    • ,
  • Stephanie C. Lin, MD

      Affiliations

    • Department of Surgery, San Francisco Veteran’s Affairs Medical Center and Pacific Vascular Research Laboratories, Division of Vascular Surgery, University of California, San Francisco, Calif
    • ,
  • Afshin Nadershahi, BS

      Affiliations

    • Department of Surgery, San Francisco Veteran’s Affairs Medical Center and Pacific Vascular Research Laboratories, Division of Vascular Surgery, University of California, San Francisco, Calif
    • ,
  • Stephanie W. Watts, PhD

      Affiliations

    • Department of Pharmacology and Toxicology, Michigan State University, East Lansing, Mich.
    • ,
  • Rajabrata Sarkar, MD, PhD

      Affiliations

    • Department of Surgery, San Francisco Veteran’s Affairs Medical Center and Pacific Vascular Research Laboratories, Division of Vascular Surgery, University of California, San Francisco, Calif
    • Corresponding Author InformationReprint requests: Rajabrata Sarkar, MD, PhD, 4150 Clement St (112G), San Francisco, CA 94121.

Received 27 June 2007 ,Accepted 1 November 2007.

References 

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 Competition of interest: none.

 Supported by a University of California, San Francisco (UCSF) Faculty Development Award and a Mentored Clinician Scientist Development Award (HL04435) from the National Institutes of Health (NIH) National Heart, Lung, and Blood Institute (NHLBI), the Lifeline Foundation, and the William J. von Leibig Foundation to Dr Sarkar. Dr Huang is the recipient of a Medical Fellowship Award from the Giannini Family Foundation. Dr Lin was supported by Nafzinger Surgical Society fellowship. Dr Watts is an Established Investigator of the American Heart Association. Additional support to Dr Sarkar was received from the Pacific Vascular Research Foundation, the UCSF Academic Senate and Committee on Research and NIH (PO1 HL70687) to Dr Watts.

PII: S0741-5214(07)01768-5

doi: 10.1016/j.jvs.2007.11.006

Journal of Vascular Surgery
Volume 47, Issue 3 , Pages 599-607 , March 2008

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