Journal of Vascular Surgery
Volume 47, Issue 3 , Pages 537-542 , March 2008

Safety and efficacy of intravenous enoxaparin for carotid endarterectomy: A prospective randomized pilot trial

  • Afshin Assadian, MD

      Affiliations

    • Department of General and Vascular Surgery, Wilhelminenspital, Vienna, Austria
    • Corresponding Author InformationCorrespondence: Afshin Assadian, MD, Department of General and Vascular Surgery, Wilhelminenspital Vienna, Montleartstraße 37, A-1160 Vienna, Austria.
    • ,
  • Paul Knöbl, MD

      Affiliations

    • Department of Medicine I, Medical University, Vienna, Austria
    • ,
  • Wolfgang Hübl, MD

      Affiliations

    • Department of Laboratory Medicine, Wilhelminenspital, Vienna, Austria
    • ,
  • Christian Senekowitsch, MD

      Affiliations

    • Department of General and Vascular Surgery, Wilhelminenspital, Vienna, Austria
    • ,
  • Anton Klingler, PhD

      Affiliations

    • Assign Data Management and Biostatistics GmbH, Innsbruck, Austria.
    • ,
  • Norbert Pfaffelmeyer, MD

      Affiliations

    • Department of Neurology, Wilhelminenspital, Vienna, Austria
    • ,
  • Georg W. Hagmüller, MD

      Affiliations

    • Department of General and Vascular Surgery, Wilhelminenspital, Vienna, Austria

Received 16 July 2007 ,Accepted 27 October 2007.

  • Image Result

    Course of the anticoagulation response before carotid surgery and after an intravenous (iv) bolus of unfractionated heparin (UNF) or low-molecular-weight heparin (LMWH) at 15, 30 and 45 minutes postop

    Course of the anticoagulation response before carotid surgery and after an intravenous (iv) bolus of unfractionated heparin (UNF) or low-molecular-weight heparin (LMWH) at 15, 30 and 45 minutes postoperatively as estimated by antifactor Xa activities (IU/mL). The solid line, enoxaparin (n = 119); dotted line, UNF (n = 40). Median values are presented with interquartile ranges (whiskers). ***P < .001; **P < .01 Kruskal-Wallis test.

 Competition of interest: The study was supported by a scientific grant by Sanofi-Aventis Austria, who is the manufacturer and distributor of enoxaparin.

PII: S0741-5214(07)01759-4

doi: 10.1016/j.jvs.2007.10.055

Journal of Vascular Surgery
Volume 47, Issue 3 , Pages 537-542 , March 2008

Article Tools

* Image Usage & Resolution