Journal of Vascular Surgery
Volume 47, Issue 2 , Pages 388-394 , February 2008

Safety of catheter-directed thrombolysis for deep venous thrombosis in cancer patients

  • Hyun S. Kim, MD

      Affiliations

    • Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore Md
    • Department of Surgery, Johns Hopkins University School of Medicine, Baltimore Md
    • Corresponding Author InformationReprint requests: Hyun S. Kim, MD, 600 N Wolfe St, Blalock 545, Division of Vascular and Interventional Radiology, Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD 21287-4010.
  • ,
  • Stephen R. Preece, BA

      Affiliations

    • Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore Md
  • ,
  • James H. Black, MD

      Affiliations

    • Department of Surgery, Johns Hopkins University School of Medicine, Baltimore Md
  • ,
  • Luu D. Pham, MA

      Affiliations

    • Department of Biostatistics, Johns Hopkins University School of Medicine, Baltimore Md
  • ,
  • Michael B. Streiff, MD

      Affiliations

    • Department of Medicine, Johns Hopkins University School of Medicine, Baltimore Md.

Received 23 July 2007 ,Accepted 20 October 2007.

References 

  1. Stein PD, Beemath A, Olson RE. Trends in the incidence of pulmonary embolism and deep venous thrombosis in hospitalized patients. Am J Cardiol. 2005;95:1525–1526
  2. Deitcher SR. Cancer-related deep venous thrombosis: clinical importance, treatment challenges, and management strategies. Semin Thromb Hemost. 2003;29:247–258
  3. Trujillo-Santos J, Herrera S, Page MA, Soto MJ, Raventós A, Sánchez R, et al. Predicting adverse outcome in outpatients with acute deep vein thrombosis (findings from the RIETE Registry). J Vasc Surg. 2006;44:789–793
  4. Khorana AA, Francis CW, Culakova E, Fisher RI, Kuderer NM, Lyman GH. Thromboembolism in hospitalized neutropenic cancer patients. J Clin Oncol. 2006;24:484–490
  5. Kearon C. Natural history of venous thromboembolism. Circulation. 2003;107(23 suppl 1):122–130
  6. Büller HR, Agnelli G, Hull RD, Hyers TM, Prins MH, Raskob GE. Antithrombotic therapy for venous thromboembolic disease: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy. Chest. 2004;126(3 suppl):401S–428S
  7. Prandoni P, Lensing AWA, Prins MH, Bernardi E, Marchiori A, Bagatella P, et al. Residual venous thrombosis as a predictive factor of recurrent venous thromboembolism. Ann Intern Med. 2002;137:955–960
  8. Prandoni P, Frulla M, Sartor D, Concolato A, Girolami A. Vein abnormalities and the post-thrombotic syndrome. J Thromb Haemost. 2005;3:401–402
  9. Comerota AJ, Aldridge SC. Thrombolytic therapy for deep venous thrombosis: a clinical review. Can J Surg. 1993;36:359–364
  10. Comerota AJ, Throm RC, Mathias SD, Haughton S, Mewissen M. Catheter-directed thrombolysis for iliofemoral deep venous thrombosis improves health-related quality of life. J Vasc Surg. 2000;32:130–137
  11. Mewissen MW, Seabrook GR, Meissner MH, Cynamon J, Labropoulos N, Haughton SH. Catheter-directed thrombolysis for lower extremity deep venous thrombosis: report of a national multicenter registry. Radiology. 1999;211:39–49
  12. Segal JB, Bolger DT, Jenckes MW, Krishnan JA, Streiff MB, Eng J, et al. Outpatient therapy with low molecular weight heparin for the treatment of venous thromboembolism: a review of efficacy, safety, and costs. Am J Med. 2003;115:298–308
  13. Wells PS, Forster AJ. Thrombolysis in deep vein thrombosis: is there still an indication?. Thromb Haemost. 2001;86:499–508
  14. Hutten BA, Prins MH, Gent M, Ginsberg J, Tijssen JGP, Buller HR. Incidence of recurrent thromboembolic and bleeding complications among patients with venous thromboembolism in relation to both malignancy and achieved international normalized ratio: a retrospective analysis. J Clin Oncol. 2000;18:3078–3083
  15. Prandoni P, Lensing AWA, Piccioli A, Bernardi E, Simioni P, Girolami B, et al. Recurrent venous thromboembolism and bleeding complications during anticoagulant treatment in patients with cancer and venous thrombosis. Blood. 2002;100:3484–3488
  16. Schweizer J, Kirch W, Koch R, Elix H, JHellner G, Forkmann L, et al. Short- and long- term results after thrombolytic treatment of deep venous thrombosis. J Am Coll Cardiol. 2000;36:1336–1343
  17. Schwieder G, Grimm W, Siemens HJ, Flor B, Hilden A, Gmelin E, et al. Intermittent regional therapy with rt-PA is not superior to systemic thrombolysis in deep vein thrombosis (DVT)–a German multicenter trial. Thromb Haemost. 1995;74:1240–1243
  18. Sillesen H, Just S, Jørgensen M, Baekgaard N. Catheter directed thrombolysis for treatment of ilio-femoral deep venous thrombosis is durable, preserves venous valve function and may prevent chronic venous insufficiency. Eur J Vasc Endovasc Surg. 2005;30:556–562
  19. Porter JM, Meneta GL International Consensus Committee on Chronic Venous Disease. Reporting standards in venous disease: an update. J Vasc Surg. 1995;21:635–645
  20. Omary RA, Bettmann MA, Cardella JF, Bakal CW, Schwartzberg MS, Sacks D, et al. Quality improvement guidelines for the reporting and archiving of interventional radiology procedures. J Vasc Interv Radiol. 2003;14:293S–295S
  21. Angle JF, Matsumoto AH, Al Shammari M, Hagspiel KD, Spinosa DJ, Humphries JE. Transcatheter regional urokinase therapy in the management of inferior vena cava thrombosis. J Vasc Interv Radiol. 1998;9:917–925
  22. Cesaro S, Paris M, Corrò R, Svaluto G, Zanon GF, Gamba P, et al. Successful treatment of a catheter-related right atrial thrombosis with recombinant tissue plasminogen activator and heparin. Support Care Cancer. 2002;10:253–255
  23. de Gregorio Ariza MA, Gamboa P, Gimeno MJ, Alfonso E, Mainar A, Medrano J, et al. Percutaneous treatment of superior vena cava syndrome using metallic stents. Eur Radiol. 2003;13:853–862
  24. Griffin D, Martino MA, Hoffman MS. Superior vena cava syndrome during chemotherapy for stage 3c fallopian tube adenocarcinoma. Gynecol Oncol. 2004;93:257–259
  25. Sakai K, Ochiai H, Katayama N, Nakamura K, Arataki K, Kido T, et al. Catheter interventional therapy in an elderly patient with deep vein thrombosis and a brain tumor. Jpn Heart J. 2004;45:709–713
  26. Savage SA, Young G, Reaman GH. Catheter-directed thrombolysis in a child with acute lymphoblastic leukemia and extensive deep vein thrombosis. Med Pediatr Oncol. 2000;34:215–217
  27. Schindler J, Bona RD, Chen HH, Feingold JM, Edwards RL, Tutschka PJ, et al. Regional thrombolysis with urokinase for central venous catheter-related thrombosis in patients undergoing high-dose chemotherapy with autologous blood stem cell rescue. Clin Appl Thromb Hemost. 1999;5:25–29
  28. Volkow P, Cornejo-Juárez P, Arizpe-Bravo AB, García-Méndez J, Baltazares-Lipp E, Pérez-Padilla R. Catheter-related septic thrombophlebitis of the great central veins successfully treated with low-dose streptokinase thrombolysis and antimicrobials. Thromb J. 2005;22:11
  29. Mikkola KM, Patel SR, Parker JA, Grodstein F, Goldhaber SZ. Attenuation over 24 hours of the efficacy of thrombolysis of pulmonary embolism among patients with cancer. Am Heart J. 1997;134:603–607
  30. Kim HS, Patra A, Paxton BE, Khan J, Streiff MB. Adjunctive percutaneous mechanical thrombectomy for lower-extremity deep vein thrombosis: clinical and economic outcomes. J Vasc Interv Radiol. 2006;17:1099–1104

 Competition of interest: none.

PII: S0741-5214(07)01694-1

doi: 10.1016/j.jvs.2007.10.033

Journal of Vascular Surgery
Volume 47, Issue 2 , Pages 388-394 , February 2008