Journal of Vascular Surgery
Volume 46, Issue 6 , Pages 1130-1137 , December 2007

Intraplaque hemorrhage assessed by high-resolution magnetic resonance imaging and C-reactive protein in carotid atherosclerosis

  • Luciano Cabral Albuquerque, MD, ScD

      Affiliations

    • Division of Adult Cardiovascular Surgery, Cardiovascular Sciences of the Federal University of Rio Grande do Sul, Puerto Alegre, Brazil
    • ,
  • Luciane Barreneche Narvaes, MD

      Affiliations

    • Division of Adult Cardiovascular Surgery, Cardiovascular Sciences of the Federal University of Rio Grande do Sul, Puerto Alegre, Brazil
    • ,
  • Aluísio Antunes Maciel, MD

      Affiliations

    • Division of Pathology, Cardiovascular Sciences of the Federal University of Rio Grande do Sul, Puerto Alegre, Brazil
    • ,
  • Henrique Staub, MD, ScD

      Affiliations

    • Division of Rheumatology, Cardiovascular Sciences of the Federal University of Rio Grande do Sul, Puerto Alegre, Brazil
    • ,
  • Maurício Friedrich, MD

      Affiliations

    • Division of Neurology, Cardiovascular Sciences of the Federal University of Rio Grande do Sul, Puerto Alegre, Brazil
    • ,
  • João Rubião Hoefel Filho, MD, ScD

      Affiliations

    • Center for Diagnostic Imaging of the Pontifical Catholic University of Rio Grande do Sul’s São Lucas Hospital, Puerto Alegre, Brazil
    • ,
  • Maurício Barreira Marques, MD

      Affiliations

    • Center for Diagnostic Imaging of the Pontifical Catholic University of Rio Grande do Sul’s São Lucas Hospital, Puerto Alegre, Brazil
    • ,
  • Luis Eduardo Rohde, MD, ScD

      Affiliations

    • Cardiology Division of the Hospital de Clínicas de Porto Alegre, Puerto Alegre, Brazil.
    • Corresponding Author InformationCorrespondence: Luis E. Rohde, MD, Post-graduate Program in Cardiology and Cardiovascular Sciences of the Federal University of Rio Grande do Sul, Rua Ramiro Barcelos 2350, Rm 2060, Second Floor, Porto Alegre 90035 903 Brazil.

Received 15 March 2007 ,Accepted 3 July 2007.

  • Image Result

    Association between the presence of hyperintense signal on high-resolution magnetic resonance imaging (MRI) and neurologic symptoms as evaluated by an independent neurologist unaware of MRI findings.

    Association between the presence of hyperintense signal on high-resolution magnetic resonance imaging (MRI) and neurologic symptoms as evaluated by an independent neurologist unaware of MRI findings.

  • Image Result

    Absence of association between the presence of hyperintense signal on high-resolution magnetic resonance imaging (MRI) and different degrees of angiographic stenosis.

    Absence of association between the presence of hyperintense signal on high-resolution magnetic resonance imaging (MRI) and different degrees of angiographic stenosis.

  • Image Result

    A, Representative example of high-resolution magnetic resonance imaging shows absence of hyperintense signal (white arrows) on sagittal and (B) axial views. C and D, Histologic findings (hematoxylin a

    A, Representative example of high-resolution magnetic resonance imaging shows absence of hyperintense signal (white arrows) on sagittal and (B) axial views. C and D, Histologic findings (hematoxylin and eosin staining) from the same patient show the absence of intraplaque hemorrhage.

  • Image Result
    A, Representative example of high-resolution magnetic resonance imaging shows hyperintense signal (white arrows) on sagittal and (B) axial views. C, Histologic findings of intraplaque hemorrhage from

    A, Representative example of high-resolution magnetic resonance imaging shows hyperintense signal (white arrows) on sagittal and (B) axial views. C, Histologic findings of intraplaque hemorrhage from the same patient, recognized as extracellular and intracellular metahemoglobin on (D) hematoxylin and eosin staining (reddish-orange coloring).

  • Image Result
    A, High-sensitivity C-reactive protein (hs-CRP) levels according to different degrees of angiographic stenosis. B, Levels of hs-CRP according to the presence of stable or unstable neurologic symptoms

    A, High-sensitivity C-reactive protein (hs-CRP) levels according to different degrees of angiographic stenosis. B, Levels of hs-CRP according to the presence of stable or unstable neurologic symptoms and the presence of hyperintense signal on high-resolution magnetic resonance imaging.

 Competition of interest: none.

PII: S0741-5214(07)01252-9

doi: 10.1016/j.jvs.2007.07.041

Journal of Vascular Surgery
Volume 46, Issue 6 , Pages 1130-1137 , December 2007

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