Journal of Vascular Surgery
Volume 46, Issue 5 , Pages 883-890.e1 , November 2007

Cost-effectiveness of conventional and endovascular repair of abdominal aortic aneurysms: Results of a randomized trial

  • Monique Prinssen, MD, PhD

      Affiliations

    • Division of Vascular Surgery, Department of Surgery, University Medical Center Utrecht, Utrecht, The Netherlands
  • ,
  • Erik Buskens, MD, PhD

      Affiliations

    • Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands and Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
    • Corresponding Author InformationReprint requests: Erik Buskens, MD, PhD, Department of Epidemiology, University Medical Center Groningen, University of Groningen, PO Box 30,001, 9700 RB Groningen, The Netherlands.
  • ,
  • Sjors E. de Jong, MD, PhD

      Affiliations

    • Department of Vascular Surgery, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
  • ,
  • Jacob Buth, MD

      Affiliations

    • Department of Surgery, Catharina Hospital Eindhoven, Eindhoven, The Netherlands
  • ,
  • Albert J. Mackaay, MD, PhD

      Affiliations

    • Department of Surgery, Meander Medical Center, Amersfoort, The Netherlands
  • ,
  • Marc R. Sambeek, MD, PhD

      Affiliations

    • Division of Vascular Surgery, Department of Surgery, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands.
  • ,
  • Jan D. Blankensteijn, MD, PhD

      Affiliations

    • Department of Vascular Surgery, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
  • ,
  • DREAM trial participants

Received 18 January 2007 ,Accepted 23 July 2007.

  • Image Result

    Utility score over time in the first postoperative year after endovascular repair (gray line) and open repair (dashed line) with 95% confidence intervals. Area under the curve equals quality-adjusted

    Utility score over time in the first postoperative year after endovascular repair (gray line) and open repair (dashed line) with 95% confidence intervals. Area under the curve equals quality-adjusted life years.

  • Image Result
    Cost-effectiveness planes for (A) quality-adjusted life years, (B) event-free years gained, and (C) life-years gained for costs of endovascular repair (ER) and open repair (OR). The cost-effectiveness

    Cost-effectiveness planes for (A) quality-adjusted life years, (B) event-free years gained, and (C) life-years gained for costs of endovascular repair (ER) and open repair (OR). The cost-effectiveness plane consists of four quadrants. A dot to the right of the y-axis means that ER yields a better outcome, whereas a dot on the left side means the OR yields a better outcome. Likewise, a dot above the x-axis means that the costs of ER are higher, whereas a dot below the x-axis implies that OR is more expensive. The lower right and upper left quadrant would indicate that both costs and effects are favorable (dominant) for ER and OR, respectively. The percentages represent the proportion of bootstrap replication in which the clinical outcome is favorable for open repair. A, The oblique line indicates a societal willingness to pay a threshold of €25,000 per quality-adjusted life year.

 Additional material for this article may be found online at www.jvascsurg.org.

 Competition of interest: none.

PII: S0741-5214(07)01196-2

doi: 10.1016/j.jvs.2007.07.033

Journal of Vascular Surgery
Volume 46, Issue 5 , Pages 883-890.e1 , November 2007