Journal of Vascular Surgery
Volume 46, Issue 5 , Pages 841-845 , November 2007

Increased aortic arch calcification in patients older than 75 years: Implications for carotid artery stenting in elderly patients

Presented at the 2007 Peripheral Vascular Surgery Society Spring Meeting, Baltimore, Md, June 6-9, 2007.

  • Hernan A. Bazan, MD

      Affiliations

    • Department of Surgery, Yale University School of Medicine, New Haven, Conn
    • Corresponding Author InformationReprint requests: Hernan A. Bazan, MD, Department of Surgery, Section of Vascular Surgery, Louisiana State University Health Sciences Center in New Orleans, 533 Bolivar Street, Room 524, New Orleans, LA 70112.
  • ,
  • Sanjeev Pradhan, MD

      Affiliations

    • Department of Surgery, Yale University School of Medicine, New Haven, Conn
  • ,
  • Hamid Mojibian, MD

      Affiliations

    • Department of Diagnostic Imaging, Yale University School of Medicine, New Haven, Conn
  • ,
  • Tassos Kyriakides, PhD

      Affiliations

    • VA Connecticut Healthcare Systems, West Haven, Conn.
  • ,
  • Alan Dardik, MD, PhD

      Affiliations

    • Department of Surgery, Yale University School of Medicine, New Haven, Conn
    • VA Connecticut Healthcare Systems, West Haven, Conn.

Received 23 April 2007 ,Accepted 27 June 2007.

  • Image Result

    Quantification of aortic arch calcium content. Vitrea software (version 2.0) was used to apply the Agatston coronary calcium score. A, The aortic arch of a 54-year-old patient without significant arch

    Quantification of aortic arch calcium content. Vitrea software (version 2.0) was used to apply the Agatston coronary calcium score. A, The aortic arch of a 54-year-old patient without significant arch calcium. B, A representative aortic arch of a 77-year-old patient demonstrates diffuse aortic arch calcium content (arrows).

  • Image Result
    Increased aortic arch calcium content correlates with increasing patient age. A, Positive correlation between age and aortic arch calcium content by linear regression (r2 = 0.34; P < .0001). B, The me

    Increased aortic arch calcium content correlates with increasing patient age. A, Positive correlation between age and aortic arch calcium content by linear regression (r2 = 0.34; P < .0001). B, The mean calcium score for patients increases by decade in a highly significant fashion (P < .001). *Significant difference compared with patients younger than 50 years of age (P = .03 [70-79 years] or P < .001 [≥80 years]; Scheffé post hoc test). C, Increased arch calcification in patients 75 years or older compared with those less than 75 years old (*P < .001).

  • Image Result
    Aortic arch elongation is associated with a higher calcium content compared with nonelongated arches. *Significant difference (P = .01; unpaired t test).

    Aortic arch elongation is associated with a higher calcium content compared with nonelongated arches. *Significant difference (P = .01; unpaired t test).

 Competition of interest: none.This material is the result of work partially supported by the National Institutes of Health Career Development award HL079927/American Vascular Association William J. von Liebig Award, as well as with resources and the use of facilities at the VA Connecticut Healthcare System, West Haven.CME article

PII: S0741-5214(07)01183-4

doi: 10.1016/j.jvs.2007.06.048

Journal of Vascular Surgery
Volume 46, Issue 5 , Pages 841-845 , November 2007