Journal of Vascular Surgery
Volume 46, Issue 4 , Pages 687-693 , October 2007

The interleukin-10-1082 ‘A’ allele and abdominal aortic aneurysms

  • Matthew J. Bown, MD, MRCS

      Affiliations

    • Department of Cardiovascular Sciences, University of Leicester, Leicester, UK
    • Corresponding Author InformationReprint requests: Matthew J. Bown, MD, MRCS, Vascular Surgery Research Group, Robert Kilpatrick Clinical Sciences Building, Leicester Royal Infirmary, Leicester, LE2 7LX, UK.
    • ,
  • Geraint M. Lloyd, MB, ChB, MRCS

      Affiliations

    • Department of Cardiovascular Sciences, University of Leicester, Leicester, UK
    • ,
  • Rebecca M. Sandford, MB, ChB, MRCS

      Affiliations

    • Department of Cardiovascular Sciences, University of Leicester, Leicester, UK
    • ,
  • John R. Thompson, BSc, PhD

      Affiliations

    • Department of Health Sciences, University of Leicester, Leicester, UK.
    • ,
  • Nicholas J.M. London, MD, FRCS, FRCP

      Affiliations

    • Department of Cardiovascular Sciences, University of Leicester, Leicester, UK
    • ,
  • Nilesh J. Samani, MD, FRCP

      Affiliations

    • Department of Cardiovascular Sciences, University of Leicester, Leicester, UK
    • ,
  • Robert D. Sayers, MD, FRCS

      Affiliations

    • Department of Cardiovascular Sciences, University of Leicester, Leicester, UK

References 

  1. Campa JS, Greenhalgh RM, Powell JT. Elastin degradation in abdominal aortic aneurysms. Atherosclerosis. 1987;65:13–21
  2. Satta J, Juvonen T, Haukipuro K, Juvonen M, Kairaluoma MI. Increased turnover of collagen in abdominal aortic aneurysms, demonstrated by measuring the concentration of the amino terminal propeptide of type III procollagen in peripheral and aortal blood samples. J Vasc Surg. 1995;22:155–160
  3. Thompson RW, Liao S, Curci JA. Vascular smooth muscle cell apoptosis in abdominal aortic aneurysms. Coron Artery Dis. 1997;8:623–631
  4. Shah PK. Inflammation, metalloproteinases, and increased proteolysis: an emerging pathophysiological paradigm in aortic aneurysm. [comment] Circulation. 1997;96:2115–2117
  5. Wojtowicz-Praga SM, Dickson RB, Hawkins MJ. Matrix metalloproteinase inhibitors. Invest New drugs. 1997;15:61–75
  6. Knox JB, Sukhova GK, Whittemore AD, Libby P. Evidence for altered balance between matrix metalloproteinases and their inhibitors in human aortic diseases. Circulation. 1997;95:205–212
  7. Newman KM, Jean-Claude J, Li H, Scholes JV, Ogata Y, Nagase H, et al. Cellular localization of matrix metalloproteinases in the abdominal aortic aneurysm wall. J Vasc Surg. 1994;20:814–820
  8. Davis VA, Persidskaia RN, Baca-Regen LM, Fiotti N, Halloran BG, Baxter BT. Cytokine pattern in aneurysmal and occlusive disease of the aorta. J Surg Res. 2001;101:152–156
  9. Shteinberg D, Halak M, Shapiro S, Kinarty A, Sobol E, Lahat N, et al. Abdominal aortic aneurysm and aortic occlusive disease: a comparison of risk factors and inflammatory response. Eur J Vasc Endovasc Surg. 2000;20:462–465
  10. Turner DM, Williams DM, Sankaran D, Lazarus M, Sinnott PJ, Hutchinson IV. An investigation of polymorphism in the interleukin-10 gene promoter. Eur J Immunogenetics. 1997;24:1–8
  11. Mehrian R, Quismorio FP, Strassmann G, Stimmler MM, Horwitz DA, Kitridou RC, et al. Synergistic effect between IL-10 and bcl-2 genotypes in determining susceptibility to systemic lupus erythematosus. Arthritis Rheum. 1998;41:596–602
  12. Eskdale J, McNicholl J, Wordsworth P, Jonas B, Huizinga T, Field M, et al. Interleukin-10 microsatellite polymorphisms and IL-10 locus alleles in rheumatoid arthritis susceptibility. Lancet. 1998;352:1282–1283
  13. Crawley E, Kay R, Sillibourne J, Patel P, Hutchinson I, Woo P. Polymorphic haplotypes of the interleukin-10 5’ flanking region determine variable interleukin-10 transcription and are associated with particular phenotypes of juvenile rheumatoid arthritis. Arthritis Rheum. 1999;42:1101–1108
  14. Bown MJ, Burton PR, Horsburgh T, Nicholson ML, Bell PR, Sayers RD. The role of cytokine gene polymorphisms in the pathogenesis of abdominal aortic aneurysms: a case-control study. J Vasc Surg. 2003;37:999–1005
  15. Bown MJ, Horsburgh T, Nicholson ML, Bell PR, Sayers RD. Cytokine gene polymorphisms and the inflammatory response to abdominal aortic aneurysm repair. Br J Surg. 2003;90:1085–1092
  16. Uitenbroek.
  17. Havranek E, Howell WM, Fussell HM, Whelan JA, Whelan MA, Pandha HS. An interleukin-10 promoter polymorphism may influence tumor development in renal cell carcinoma. J Urol. 2005;173:709–712
  18. McCarron SL, Edwards S, Evans PR, Gibbs R, Dearnaley DP, Dowe A, et al. Influence of cytokine gene polymorphisms on the development of prostate cancer. Cancer Res. 2002;62:3369–3372
  19. Giordani L, Bruzzi P, Lasalandra C, Quaranta M, Schittulli F, Della Ragione F, et al. Association of breast cancer and polymorphisms of interleukin-10 and tumor necrosis factor-alpha genes. Clin Chem. 2003;49:1664–1667
  20. Howell WM, Turner SJ, Bateman AC, Theaker JM. IL-10 promoter polymorphisms influence tumour development in cutaneous malignant melanoma. Genes Immunity. 2001;2:25–31
  21. Veraldi GF, Tasselli S, De Manzoni G, Cordiano C. Surgical treatment of abdominal aortic aneurysm with concomitant renal cell carcinoma: a single-centre experience with review of the literature. J Cardiovasc Surg (Torino). 2006;47:643–649
  22. Silverstein AD, Weizer AZ, Anderson EE. Ruptured abdominal aortic aneurysm complicated by horseshoe kidney and renal cell carcinoma. Urology. 2002;60:1108
  23. Dowson HM, Montgomery BS. Prevalence of abdominal aortic aneurysms in urology patients referred for ultrasound. [comment] Ann Royal Coll Surg Engl. 2000;82:146
  24. Ogata T, Shibamura H, Tromp G, Sinha M, Goddard KA, Sakalihasan N, et al. Genetic analysis of polymorphisms in biologically relevant candidate genes in patients with abdominal aortic aneurysms. J Vasc Surg. 2005;41:1036–1042
  25. Crow P, Shaw E, Earnshaw JJ, Poskitt KR, Whyman MR, Heather BP. A single normal ultrasonographic scan at age 65 years rules out significant aneurysm disease for life in men. Br J Surg. 2001;88:941–944
  26. Sorensen HT, Gillman MW. Matching in case-control studies. BMJ. 1995;310:329–330
  27. Duftner C, Seiler R, Klein-Weigel P, Gobel H, Goldberger C, Ihling C, et al. High prevalence of circulating CD4+CD28- T-cells in patients with small abdominal aortic aneurysms. [see comment] Arteriosclerosis, Thromb Vasc Biol. 2005;25:1347–1352
  28. Johansen K, Koepsell T. Familial tendency for abdominal aortic aneurysms. JAMA. 1986;256:1934–1936
  29. Darling RC, Brewster DC, Darling RC, LaMuraglia GM, Moncure AC, Cambria RP, et al. Are familial abdominal aortic aneurysms different?. J Vasc Surg. 1989;10:39–43
  30. Baird PA, Sadovnick AD, Yee IM, Cole CW, Cole L. Sibling risks of abdominal aortic aneurysm. Lancet. 1995;346:601–604
  31. Fatini C, Pratesi G, Sofi F, Gensini F, Sticchi E, Lari B, et al. ACE DD genotype: a predisposing factor for abdominal aortic aneurysm. Eur J Vasc Endovasc Surg. 2005;29:227–232
  32. Pola R, Gaetani E, Santoliquido A, Gerardino L, Cattani P, Serricchio M, et al. Abdominal aortic aneurysm in normotensive patients: association with angiotensin-converting enzyme gene polymorphism. Eur J Vasc Endovasc Surg. 2001;21:445–449
  33. Massart F, Marini F, Menegato A, Del Monte F, Nuti M, Butitta F, et al. Allelic genes involved in artery compliance and susceptibility to sporadic abdominal aortic aneurysm. J Steroid Biochem Mol Biol. 2004;92:413–418
  34. Schillinger M, Exner M, Mlekusch W, Domanovits H, Huber K, Mannhalter C, et al. Heme oxygenase-1 gene promoter polymorphism is associated with abdominal aortic aneurysm. Thromb Res. 2002;106:131–136
  35. Strauss E, Waliszewski K, Gabriel M, Zapalski S, Pawlak AL. Increased risk of the abdominal aortic aneurysm in carriers of the MTHFR 677T allele. J Appl Genetics. 2003;44:85–93
  36. Unno N, Nakamura T, Mitsuoka H, Uchiyama T, Yamamoto N, Saito T, et al. Association of a G994 −>T missense mutation in the plasma platelet-activating factor acetylhydrolase gene with risk of abdominal aortic aneurysm in Japanese. Ann Surg. 2002;235:297–302
  37. Ghilardi G, Biondi ML, Battaglioli L, Zambon A, Guagnellini E, Scorza R. Genetic risk factor characterizes abdominal aortic aneurysm from arterial occlusive disease in human beings: CCR5 Delta 32 deletion. J Vasc Surg. 2004;40:995–1000
  38. Jones GT, Phillips VL, Harris EL, Rossaak JI, van Rij AM. Functional matrix metalloproteinase-9 polymorphism (C-1562T) associated with abdominal aortic aneurysm. J Vasc Surg. 2003;38:1363–1367
  39. Yeung JM, Heeley M, Gray S, Lingam MK, Manning G, Nash JR, et al. Does the angiotensin-converting enzyme (ACE) gene polymorphism affect rate of abdominal aortic aneurysm expansion?. Eur J Vasc Endovasc Surg. 2002;24:69–71
  40. Tilson MD, Seashore MR. Human genetics of the abdominal aortic aneurysm. Surg Gynecol Obstet. 1984;158:129–132
  41. Majumder PP, St Jean PL, Ferrell RE, Webster MW, Steed DL. On the inheritance of abdominal aortic aneurysm. Am J Human Genetics. 1991;48:164–170
  42. Powell JT, Greenhalgh RM. Multifactorial inheritance of abdominal aortic aneurysm. Eur J Vasc Surg. 1987;1:29–31
  43. Verloes A, Sakalihasan N, Limet R, Koulischer L. Genetic aspects of abdominal aortic aneurysm. Ann NY Acad Sci. 1996;800:44–55
  44. van Keulen CJ, van den Akker E, van den Berg FG, Pals G, Rauwerda JA. The role of type III collagen in family members of patients with abdominal aortic aneurysms. Eur J Vasc Endovasc Surg. 2000;20:379–385
  45. Kuivaniemi H, Shibamura H, Arthur C, Berguer R, Cole CW, Juvonen T, et al. Familial abdominal aortic aneurysms: Collection of 233 multiplex families. J Vasc Surg. 2003;37:340–345

 Competition of interest: none.CME article

PII: S0741-5214(07)00996-2

doi: 10.1016/j.jvs.2007.06.025

Journal of Vascular Surgery
Volume 46, Issue 4 , Pages 687-693 , October 2007

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