Journal of Vascular Surgery
Volume 46, Issue 3 , Pages 449-454 , September 2007

Fibrinogen and high-sensitive C-reactive protein as serologic predictors for perioperative cerebral microembolic lesions after carotid endarterectomy

  • Peter Heider, MD

      Affiliations

    • Department of Vascular Surgery, Rechts der Isar Medical Center, Technical University of Munich, Munich, Germany
    • Corresponding Author InformationReprint requests: Dr Peter Heider, Rechts der Isar Medical Center, Technical University of Munich, Ismaninger Str 22, D-81675 Munich, Germany.
    • ,
  • Holger Poppert, MD

      Affiliations

    • Department of Neurology, Rechts der Isar Medical Center, Technical University of Munich, Munich, Germany
    • ,
  • Oliver Wolf, MD

      Affiliations

    • Department of Vascular Surgery, Rechts der Isar Medical Center, Technical University of Munich, Munich, Germany
    • ,
  • Thomas Liebig, MD

      Affiliations

    • Department of Neuroradiology, Rechts der Isar Medical Center, Technical University of Munich, Munich, Germany
    • ,
  • Jaroslav Pelisek, PhD

      Affiliations

    • Department of Vascular Surgery, Rechts der Isar Medical Center, Technical University of Munich, Munich, Germany
    • ,
  • Tibor Schuster, PhD

      Affiliations

    • Institute of Epidemiology and Medical Statistics, Rechts der Isar Medical Center, Technical University of Munich, Munich, Germany.
    • ,
  • Hans H. Eckstein, MD

      Affiliations

    • Department of Vascular Surgery, Rechts der Isar Medical Center, Technical University of Munich, Munich, Germany

Received 23 March 2007 ,Accepted 14 May 2007.

  • Image Result

    A postoperative diffusion-weighted image shows a lesion (arrows) in the right parietal-cortical region.

    A postoperative diffusion-weighted image shows a lesion (arrows) in the right parietal-cortical region.

  • Image Result

    Forest plot for new cerebral ischemic lesions subject to patient characteristics, risk factors, medication, and degree of stenosis. OR, Odds ratio; CI, confidence interval; ACE, angiotensin-converting

    Forest plot for new cerebral ischemic lesions subject to patient characteristics, risk factors, medication, and degree of stenosis. OR, Odds ratio; CI, confidence interval; ACE, angiotensin-converting enzyme.

  • Image Result
    Box plots demonstrate the mean values of fibrinogen (mg/dL) in patients with (1) and without (0) new cerebral lesion (P < .001). The horizontal line in the middle of each box indicates the median; the

    Box plots demonstrate the mean values of fibrinogen (mg/dL) in patients with (1) and without (0) new cerebral lesion (P < .001). The horizontal line in the middle of each box indicates the median; the top and bottom borders of the box mark the 75th and 25th percentiles, respectively; and the whiskers mark the 90th and 10th percentiles.

  • Image Result
    Box plots demonstrate the mean values of C-reactive protein (mg/dL) in patients with (1) and without (0) a new cerebral lesion (P = .625). The top and bottom borders of the box mark the 75th and 25th

    Box plots demonstrate the mean values of C-reactive protein (mg/dL) in patients with (1) and without (0) a new cerebral lesion (P = .625). The top and bottom borders of the box mark the 75th and 25th percentiles, respectively; and the whiskers mark the 90th and 10th percentiles.

  • Image Result
    Box plots demonstrate the mean values of high-sensitive CRP (mg/dl) in patients with (1) and without (0) new cerebral lesion (P = .004). The horizontal line in the middle of each box indicates the med

    Box plots demonstrate the mean values of high-sensitive CRP (mg/dl) in patients with (1) and without (0) new cerebral lesion (P = .004). The horizontal line in the middle of each box indicates the median; the top and bottom borders of the box mark the 75th and 25th percentiles, respectively; and the whiskers mark the 90th and 10th percentiles.

  • Image Result
    Odds ratios (OR) and 95% confidence intervals (CI) for new cerebral lesions for fibrinogen, C-reactive protein (CRP), and high-sensitive C-reactive protein (hsCRP) in patients after carotid endarterec

    Odds ratios (OR) and 95% confidence intervals (CI) for new cerebral lesions for fibrinogen, C-reactive protein (CRP), and high-sensitive C-reactive protein (hsCRP) in patients after carotid endarterectomy.

 Competition of interest: none.

 Financial support for this study was provided by the Commission of Clinical Research, Rechts der Isar Medical Center, Technical University of Munich (Kommission für Klinische Forschung, KKF-Nr.: 8744652).

PII: S0741-5214(07)00963-9

doi: 10.1016/j.jvs.2007.05.035

Journal of Vascular Surgery
Volume 46, Issue 3 , Pages 449-454 , September 2007

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