Journal of Vascular Surgery
Volume 46, Issue 1 , Pages 62-70 , July 2007

Prognostic value of ankle-brachial index and dobutamine stress echocardiography for cardiovascular morbidity and all-cause mortality in patients with peripheral arterial disease

Results of this study were presented at Sixteenth European Chapter Congress of the International Union of Angiology, EUROCHAP 2005, Glasgow, United Kingdom, Oct 25-27, 2005.

  • Mallik R. Thatipelli, MBBS

      Affiliations

    • Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minn
  • ,
  • Patricia A. Pellikka, MD

      Affiliations

    • Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minn
  • ,
  • Robert D. McBane, MD

      Affiliations

    • Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minn
  • ,
  • Thom W. Rooke, MD

      Affiliations

    • Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minn
  • ,
  • Gabriela A. Rosales, BS

      Affiliations

    • Division of Biostatistics, Mayo Clinic, Rochester, Minn.
  • ,
  • David Hodge, BS

      Affiliations

    • Division of Biostatistics, Mayo Clinic, Rochester, Minn.
  • ,
  • Regina M. Herges, BS

      Affiliations

    • Division of Biostatistics, Mayo Clinic, Rochester, Minn.
  • ,
  • Waldemar E. Wysokinski, MD

      Affiliations

    • Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minn
    • Corresponding Author InformationReprint requests: Waldemar E. Wysokinski, MD, Division of Cardiovascular Medicine, Mayo Clinic and Foundation for Education and Research, 200 First St SW, Rochester, MN 55905.

Received 25 October 2006 ,Accepted 11 March 2007.

  • Image Result

    Kaplan-Meier analysis of (A) survival free from the first cardiovascular event and (B) overall survival, for normal ankle-brachial index (ABI, solid line), abnormal ABI (dashed line), and control grou

    Kaplan-Meier analysis of (A) survival free from the first cardiovascular event and (B) overall survival, for normal ankle-brachial index (ABI, solid line), abnormal ABI (dashed line), and control group (dotted line). The control group (expected) was constructed on the basis of age-specific and sex-specific mortality rates in the United States white population for the period of this study.

  • Image Result
    Kaplan-Meier analysis of (A and C) survival free from the first cardiovascular event and (B and D) overall survival . A and B, Positive dobutamine stress echocardiography (DSE, dashed line) and negati

    Kaplan-Meier analysis of (A and C) survival free from the first cardiovascular event and (B and D) overall survival . A and B, Positive dobutamine stress echocardiography (DSE, dashed line) and negative DSE (solid line). C and D, Abnormal DSE (dashed line), normal DSE (solid line), and control group (dotted line). The control group (expected) was constructed on the basis of age-specific and sex-specific mortality rates in the United States white population for the period of this study.

  • Image Result
    Kaplan-Meier analysis of (A) survival free from the first cardiovascular event and (B) overall survival for normal vascular studies (ankle-brachial index [ABI] ≥0.9), and mild (ABI 0.8 to 0.9), modera

    Kaplan-Meier analysis of (A) survival free from the first cardiovascular event and (B) overall survival for normal vascular studies (ankle-brachial index [ABI] ≥0.9), and mild (ABI 0.8 to 0.9), moderate (ABI 0.5 to 0.8), and severe (ABI < 0.5) peripheral arterial disease. *Only 23 (6%) patients had mild peripheral arterial disease.

  • Image Result
    Linear regression analysis of the correlation between wall motion score index at stress and ankle-brachial index values.

    Linear regression analysis of the correlation between wall motion score index at stress and ankle-brachial index values.

 Competition of interest: none.Statistical support was provided by discretionary funding from the Cardiovascular Division at Mayo Clinic.CME article

PII: S0741-5214(07)00461-2

doi: 10.1016/j.jvs.2007.03.022

Journal of Vascular Surgery
Volume 46, Issue 1 , Pages 62-70 , July 2007