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Journal of Vascular Surgery
Volume 45, Issue 6,
Supplement
, Pages A15-A24
, June 2007
Smooth muscle cell signal transduction: Implications of vascular biology for vascular surgeons
References
- . Regulation of differentiation of vascular smooth muscle cells. Physiol Rev. 1995;75:487–517
- . The role of apoptosis in vascular disease. J Pathol. 2000;190:267–280
- . Atherosclerosis--an inflammatory disease. N Engl J Med. 1999;340:115–126
- . Developmental mechanisms underlying pathology of arteries. Physiol Rev. 1990;70:1177–1209
- . Cellular, molecular and immunological mechanisms in the pathophysiology of vein graft intimal hyperplasia. Immunol Cell Biol. 2006;84:115–124
- . Immunocytochemical determination of cell type and proliferation rate in human vein graft stenoses. J Vasc Surg. 1997;25:64–73
- . Arterial smooth muscle cell heterogeneity: implications for atherosclerosis and restenosis development. Arterioscler Thromb Vasc Biol. 2003;23:1510–1520
- . Diverse origin of intimal cells: smooth muscle cells, myofibroblasts, fibroblasts, and beyond?. Circ Res. 2002;91:652–655
- Contribution of adventitial fibroblasts to neointima formation and vascular remodeling: from innocent bystander to active participant. Circ Res. 2001;89:1111–1121
- . Molecular determinants of vascular smooth muscle cell diversity. Circ Res. 2005;96:280–291
- . Myofibroblasts. I. Paracrine cells important in health and disease. Am J Physiol. 1999;277:C1–C9
- Identification of a potential role for the adventitia in vascular lesion formation after balloon overstretch injury of porcine coronary arteries. Circulation. 1996;93:2178–2187
- . Adventitial myofibroblasts contribute to neointimal formation in injured porcine coronary arteries. Circulation. 1996;94:1655–1664
- Remodeling of autologous saphenous vein grafts (The role of perivascular myofibroblasts). Circulation. 1997;95:2684–2693
- Smooth muscle-specific SM22 protein is expressed in the adventitial cells of balloon-injured rabbit carotid artery. Arterioscler Thromb Vasc Biol. 1999;19:1393–1404
- . Direct in vivo evidence demonstrating neointimal migration of adventitial fibroblasts after balloon injury of rat carotid arteries. Circulation. 2000;101:1362–1365
- . Molecular strategies to treat vascular diseases: circulating vascular progenitor cell as a potential target for prophylactic treatment of atherosclerosis. Circ J. 2003;67:983–991
- . Circulating vascular progenitor cells contribute to vascular repair, remodeling, and lesion formation. Trends Cardiovasc Med. 2003;13:249–253
- . Stem cells, vascular smooth muscle cells and atherosclerosis. Histol Histopathol. 2006;21:979–985
- Bone marrow-derived vascular cells in response to injury. J Atheroscler Thromb. 2003;10:205–210
- . Smooth muscle cell origin and its relation to heterogeneity in development and disease. Arterioscler Thromb Vasc Biol. 1999;19:1589–1594
- Smooth-muscle progenitor cells of bone marrow origin contribute to the development of neointimal thickenings in rat aortic allografts and injured rat carotid arteries. Transplantation. 2002;74:1310–1315
- . Neointimal formation by circulating bone marrow cells. Ann N Y Acad Sci. 2001;947:18–24discussion 24-15
- Hematopoietic stem cells differentiate into vascular cells that participate in the pathogenesis of atherosclerosis. Nat Med. 2002;8:403–409
- Host bone-marrow cells are a source of donor intimal smooth- muscle-like cells in murine aortic transplant arteriopathy. Nat Med. 2001;7:738–741
- . Molecular regulation of vascular smooth muscle cell differentiation in development and disease. Physiol Rev. 2004;84:767–801
- . Multiple phenotypically distinct smooth muscle cell populations exist in the adult and developing bovine pulmonary arterial media in vivo. Circ Res. 1994;75:669–681
- . Myocardin and ternary complex factors compete for SRF to control smooth muscle gene expression. Nature. 2004;428:185–189
- . The myocardin family of transcriptional coactivators: versatile regulators of cell growth, migration, and myogenesis. Genes Dev. 2006;20:1545–1556
- . The phenotypes of smooth muscle expressed in human atheroma. Ann N Y Acad Sci. 1990;598:143–158
- . Phenotypic modulation of smooth muscle cells during the formation of neointimal thickenings in the rat carotid artery after balloon injury: an electron-microscopic and stereological study. Cell Tissue Res. 1995;281:421–433
- . Mechanical strain increases smooth muscle and decreases nonmuscle myosin expression in rat vascular smooth muscle cells. Circ Res. 1996;79:1046–1053
- . Cyclic strain stress-induced mitogen-activated protein kinase (MAPK) phosphatase 1 expression in vascular smooth muscle cells is regulated by Ras/Rac-MAPK pathways. J Biol Chem. 1999;274:25273–25280
- . Mechanical stress-initiated signal transductions in vascular smooth muscle cells. Cell Signal. 2000;12:435–445
- . A transforming growth factor beta (TGFbeta) control element drives TGFbeta-induced stimulation of smooth muscle alpha-actin gene expression in concert with two CArG elements. J Biol Chem. 1997;272:10948–10956
- . Induction of smooth muscle alpha-actin in vascular smooth muscle cells by arginine vasopressin is mediated by c-Jun amino-terminal kinases and p38 mitogen-activated protein kinase. J Biol Chem. 2000;275:22537–22543
- . Endothelial cells modulate the proliferation of mural cell precursors via platelet-derived growth factor-BB and heterotypic cell contact. Circ Res. 1999;84:298–305
- . Regulation of vascular cell behavior by collagen: form is function. Circ Res. 2001;88:458–459
- Redox regulation of vascular smooth muscle cell differentiation. Circ Res. 2001;89:39–46
- . Multiple repressor pathways contribute to phenotypic switching of vascular smooth muscle cells. Am J Physiol Cell Physiol. 2007;292:C59–C69
- . Platelet-derived growth factor-BB and Ets-1 transcription factor negatively regulate transcription of multiple smooth muscle cell differentiation marker genes. Am J Physiol Heart Circ Physiol. 2004;286:H2042–H2051
- Suppression of smooth-muscle alpha-actin expression by platelet-derived growth factor in vascular smooth-muscle cells involves Ras and cytosolic phospholipase A2. Biochem J. 1997;327:709–716
- . Regulation of smooth muscle alpha-actin promoter by vasopressin and platelet-derived growth factor in rat aortic vascular smooth muscle cells. Circ Res. 1994;75:1126–1130
- . Platelet-derived growth factor-BB-induced suppression of smooth muscle cell differentiation. Circ Res. 1992;71:1525–1532
- . Platelet-derived growth factor regulates actin isoform expression and growth state in cultured rat aortic smooth muscle cells. J Cell Physiol. 1990;142:635–642
- . Platelet-derived growth factor-induced destabilization of smooth muscle alpha-actin mRNA. J Cell Physiol. 1990;145:391–397
- . Kruppel-like factor 4 abrogates myocardin-induced activation of smooth muscle gene expression. J Biol Chem. 2005;280:9719–9727
- . Control of SRF binding to CArG box chromatin regulates smooth muscle gene expression in vivo. J Clin Invest. 2006;116:36–48
- . Insulin receptor substrate-1/SHP-2 interaction, a phenotype-dependent switching machinery of insulin-like growth factor-I signaling in vascular smooth muscle cells. J Biol Chem. 2004;279:40807–40818
- . Changes in the balance of phosphoinositide 3-kinase/protein kinase B (Akt) and the mitogen-activated protein kinases (ERK/p38MAPK) determine a phenotype of visceral and vascular smooth muscle cells. J Cell Biol. 1999;145:727–740
- Targeted overexpression of IGF-I evokes distinct patterns of organ remodeling in smooth muscle cell tissue beds of transgenic mice. J Clin Invest. 1997;100:1425–1439
- . Localization of insulin-like growth factor I and inhibition of coronary smooth muscle cell growth by somatostatin analogues in human coronary smooth muscle cells (A potential treatment for restenosis?). Circulation. 1994;89:1511–1517
- . Induction of insulin-like growth factor I messenger RNA in rat aorta after balloon denudation. Circ Res. 1990;66:1755–1760
- . In vivo proliferation of rat vascular smooth muscle in relation to diabetes mellitus insulin-like growth factor I and insulin. Diabetologia. 1992;35:104–108
- . The role of Src kinase in insulin-like growth factor-dependent mitogenic signaling in vascular smooth muscle cells. J Biol Chem. 2006;281:25041–25053
- . The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature. 1993;362:801–809
- . Antisense basic fibroblast growth factor alters the time course of mitogen-activated protein kinase in arterialized vein graft remodeling. J Vasc Surg. 2003;37:866–873
- . Mammalian MAP kinase signalling cascades. Nature. 2001;410:37–40
- The chemotactic and mitogenic effects of platelet-derived growth factor-BB on rat aorta smooth muscle cells are inhibited by basic fibroblast growth factor. J Cell Sci. 2000;113:2855–2863
- Expression of heparin-binding epidermal growth factor-like growth factor in neointimal cells induced by balloon injury in rat carotid arteries. Arterioscler Thromb Vasc Biol. 1996;16:1524–1531
- Glucocorticoid inhibits thrombin-induced expression of platelet-derived growth factor A-chain and heparin-binding epidermal growth factor-like growth factor in human aortic smooth muscle cells. J Biol Chem. 1993;268:22941–22947
- . Shear stress-stimulated endothelial cells induce smooth muscle cell chemotaxis via platelet-derived growth factor-BB and interleukin-1alpha. J Vasc Surg. 2005;41:321–331
- Sustained orbital shear stress stimulates smooth muscle cell proliferation via the extracellular signal-regulated protein kinase 1/2 pathway. J Vasc Surg. 2005;42:772–780
- . Crosstalk between protein kinase A and growth factor receptor signaling pathways in arterial smooth muscle. Cell Signal. 1999;11:465–477
- . The MAPK signaling cascade. Faseb J. 1995;9:726–735
- . Inhibition of growth factor-induced protein synthesis by a selective MEK inhibitor in aortic smooth muscle cells. J Biol Chem. 1996;271:16047–16052
- The mitogen-activated protein kinase pathway can mediate growth inhibition and proliferation in smooth muscle cells (Dependence on the availability of downstream targets). J Clin Invest. 1997;100:875–885
- . Smooth muscle cell migration and proliferation are mediated by distinct phases of activation of the intracellular messenger mitogen-activated protein kinase. J Vasc Surg. 1998;27:117–125
- . Recent progress in characterization of protein kinase cascades for phosphorylation of ribosomal protein S6. Biochim Biophys Acta. 1991;1092:350–357
- . The MAP kinase cascade is essential for diverse signal transduction pathways. Trends Biochem Sci. 1993;18:128–131
- . Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation. Cell. 1995;80:179–185
- . Regulation of transcription by MAP kinase cascades. Curr Opin Cell Biol. 1996;8:205–215
- . Mitogen-activated protein kinase pathways. Curr Opin Cell Biol. 1997;9:180–186
- . Signal transduction through MAP kinase cascades. Adv Cancer Res. 1998;74:49–139
- . Signaling--2000 and beyond. Cell. 2000;100:113–127
- . Advances in protein kinase B signalling: AKTion on multiple fronts. Trends Biochem Sci. 2004;29:233–242
- . PKB binding proteins (Getting in on the Akt). Cell. 2002;111:293–303
- . The phosphoinositide 3-kinase pathway. Science. 2002;296:1655–1657
- . The phosphatidylinositol 3-Kinase AKT pathway in human cancer. Nat Rev Cancer. 2002;2:489–501
- . Protein kinase B (PKB/Akt)--a key regulator of glucose transport?. FEBS Lett. 2001;492:199–203
- . Role of Akt signaling in vascular homeostasis and angiogenesis. Circ Res. 2002;90:1243–1250
- Regulation of endothelium-derived nitric oxide production by the protein kinase Akt. Nature. 1999;399:597–601
- Akt controls vascular smooth muscle cell proliferation in vitro and in vivo by delaying G1/S exit. Circ Res. 2003;93:1059–1065
- . The role of phosphoinositide-3 kinase and PTEN in cardiovascular physiology and disease. J Mol Cell Cardiol. 2004;37:449–471
- . Cell shape, cytoskeletal tension, and RhoA regulate stem cell lineage commitment. Dev Cell. 2004;6:483–495
- Tensional homeostasis and the malignant phenotype. Cancer Cell. 2005;8:241–254
- . Statins prevent pulsatile stretch-induced proliferation of human saphenous vein smooth muscle cells via inhibition of Rho/Rho-kinase pathway. Cardiovasc Res. 2005;68:475–482
- . Rho and vascular disease. Atherosclerosis. 2005;183:1–16
- . Rho expression and activation in vascular smooth muscle cells. Cell Motil Cytoskeleton. 2004;59:189–200
- . A role for rho in smooth muscle phenotypic regulation. Ann N Y Acad Sci. 2001;947:316–322
- . Rho kinase-induced nuclear translocation of ERK1/ERK2 in smooth muscle cell mitogenesis caused by serotonin. Circ Res. 2004;95:579–586
- Role of Rho-associated kinase in neointima formation after vascular injury. Circulation. 2001;103:284–289
- . Smooth muscle differentiation marker gene expression is regulated by RhoA-mediated actin polymerization. J Biol Chem. 2001;276:341–347
- . Regulation of smooth muscle cell growth in injured artery. J Cardiovasc Pharmacol. 1989;14(suppl 6):S12–S15
- . TGF-beta1 generates a specific multicomponent extracellular matrix in human coronary SMC. Eur J Clin Invest. 2006;36:473–482
- . Smooth muscle cell growth factors. Prog Growth Factor Res. 1991;3:177–206
- Angiotensin II type 1 receptor participates in extracellular matrix production in the late stage of remodeling after vascular injury. Cardiovasc Res. 2003;59:200–211
- . Basic fibroblast growth factor decreases elastin gene transcription in aortic smooth muscle cells. J Cell Biochem. 2002;85:592–600
- . The extracellular matrix can regulate vascular cell migration, proliferation, and survival: relationships to vascular disease. Int J Exp Pathol. 2000;81:173–182
- . Progression of atheroma: a struggle between death and procreation. Arterioscler Thromb Vasc Biol. 2002;22:1370–1380
- . Interactions between growth factor receptors and adhesion molecules: breaking the rules. Curr Opin Cell Biol. 2003;15:565–571
- Activation of Cdc42 by trans interactions of the cell adhesion molecules nectins through c-Src and Cdc42-GEF FRG. J Cell Biol. 2004;166:393–405
- Involvement of the c-Src-Crk-C3G-Rap1 signaling in the nectin-induced activation of Cdc42 and formation of adherens junctions. J Biol Chem. 2005;280:815–825
- Vav2 as a Rac-GDP/GTP exchange factor responsible for the nectin-induced, c-Src- and Cdc42-mediated activation of Rac. J Biol Chem. 2005;280:4940–4947
- Cdc42 and Rac small G proteins activated by trans-interactions of nectins are involved in activation of c-Jun N-terminal kinase, but not in association of nectins and cadherin to form adherens junctions, in fibroblasts. Genes Cells. 2003;8:481–491
- Smooth muscle cells in human coronary atherosclerosis can originate from cells administered at marrow transplantation. Proc Natl Acad Sci U S A. 2003;100:4754–4759
- . Integrin profile and in vivo homing of human smooth muscle progenitor cells. Circulation. 2004;110:2673–2677
- . Transplantation of a tissue-engineered pulmonary artery. N Engl J Med. 2001;344:532–533
- Midterm clinical result of tissue-engineered vascular autografts seeded with autologous bone marrow cells. J Thorac Cardiovasc Surg. 2005;129:1330–1338
- . Evidence for the rapid onset of apoptosis in medial smooth muscle cells after balloon injury. Circulation. 1997;95:981–987
- . Shear stress induces apoptosis in vascular smooth muscle cells via an autocrine Fas/FasL pathway. Biochem Biophys Res Commun. 2003;310:355–359
- . A decade of caspases. Oncogene. 2003;22:8543–8567
- . Mechanisms of caspase activation and inhibition during apoptosis. Mol Cell. 2002;9:459–470
- . Role of caspases in TNF-mediated regulation of cPLA(2). FEBS Lett. 2002;531:18–22
- . Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes. Cell. 2003;114:181–190
- . Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell. 1993;74:609–619
- . The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N Engl J Med. 1993;329:977–986
- . Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). Lancet. 1998;352:837–853
- . Enhanced arterial intimal thickening after balloon catheter injury in diabetic animals accompanied by PDGF beta-receptor overexpression of aortic media. Eur J Clin Invest. 1994;24:377–381
- . Diabetes mellitus induces accelerated growth of aortic smooth muscle cells: association with overexpression of PDGF beta-receptors. Eur J Clin Invest. 1993;23:84–90
- . Latent transforming growth factor-beta binding protein-1, a component of latent transforming growth factor-beta complex, accelerates the migration of aortic smooth muscle cells in diabetic rats through integrin-beta3. Diabetes. 2003;52:824–828
- Glucose or diabetes activates p38 mitogen-activated protein kinase via different pathways. J Clin Invest. 1999;103:185–195
- . Effect of glucose on insulin-like growth factor binding protein-4 proteolysis. Endocrinology. 1998;139:44–50
- . Targeted disruption of the PAPP-A gene is associated with diminished smooth muscle cell response to insulin-like growth factor-I and resistance to neointimal hyperplasia following vascular injury. Endocrinology. 2006;147:5634–5640
- Integrins as unique receptors for vascular control. J Vasc Res. 2003;40:211–233
- Management of in-sent restenosis after carotid artery stenting in high-risk patients. J Vasc Surg. 2006;43:305–312
- . Outcomes of 6906 patients undergoing percutaneous coronary intervention in the era of drug-eluting stents (Report of the DEScover Registry). Circulation. 2006;14;114:2154–2162
- Sirolimus-eluting stents versus standard stents in patients with stenosis in a native coronary artery. N Engl J Med. 2003;349:1315–1323
- Sustained activation of the JNK cascade and rapamycin-induced apoptosis are suppressed by p53/p21(Cip1). Mol Cell. 2003;11:1491–1501
- . Rapamycin inhibits vascular smooth muscle cell migration. J Clin Invest. 1996;98:2277–2283
- . Caveolin-1-deficient aortic smooth muscle cells show cell autonomous abnormalities in proliferation, migration, and endothelin-based signal transduction. Am J Physiol Heart Circ Physiol. 2006;290:H2393–H2401
- . Effect of gene delivery of NOS isoforms on intimal hyperplasia and endothelial regeneration after balloon injury. Gene Ther. 2007;14:396–404
- . Gene transfer into normal and atherosclerotic human blood vessels. Circ Res. 1998;82:1243–1252
- . Gene therapy for cardiovascular disease. Circulation. 1995;91:541–548
Competition of interest: none.This material is the result of work partially supported by National Institutes of Health awards 1 K08 HL079927 (A. D.) and 1 F32 HL086086 (T. N. F.), the American Vascular Association William J. von Liebig Award, as well as with resources and the use of facilities at the VA Connecticut Healthcare System, West Haven, Connecticut.
PII: S0741-5214(07)00353-9
doi: 10.1016/j.jvs.2007.02.061
© 2007 The Society for Vascular Surgery. Published by Elsevier Inc. All rights reserved.
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Journal of Vascular Surgery
Volume 45, Issue 6,
Supplement
, Pages A15-A24
, June 2007
