Journal of Vascular Surgery
Volume 45, Issue 5 , Pages 885-890 , May 2007

Five-year report of a multicenter controlled clinical trial of open versus endovascular treatment of abdominal aortic aneurysms

  • Brian G. Peterson, MD

      Affiliations

    • Saint Louis University, St. Louis, Mo
  • ,
  • Jon S. Matsumura, MD

      Affiliations

    • Northwestern University, Chicago, Ill
    • Corresponding Author InformationReprint requests: Jon S. Matsumura, MD, Department of Surgery, Northwestern University Feinberg School of Medicine, Suite 10-105, 251 E. Huron St, Chicago, IL 60611.
  • ,
  • David C. Brewster, MD

      Affiliations

    • Massachusetts General Hospital, Boston, Mass
  • ,
  • Michel S. Makaroun, MD

      Affiliations

    • University of Pittsburgh, Pittsburgh, Pa
  • ,
  • Excluder Bifurcated Endoprosthesis Investigators

Received 12 July 2006 ,Accepted 8 January 2007.

  • Image Result

    Curves show the time-related accumulation of major adverse events (MAE) within the control (dashed) and test (solid) groups estimated by the Nelson nonparametric method. Through the 60-month follow-up

    Curves show the time-related accumulation of major adverse events (MAE) within the control (dashed) and test (solid) groups estimated by the Nelson nonparametric method. Through the 60-month follow-up period, the total mean cumulative MAE for control subjects was 3.2 events/subject compared with test subjects with 2.4 events/subject.

  • Image Result
    Mean cumulative function (MCF) difference in major adverse events (MAE) between test and control groups. Error bars represent 95% confidence limits.

    Mean cumulative function (MCF) difference in major adverse events (MAE) between test and control groups. Error bars represent 95% confidence limits.

  • Image Result
    Kaplan-Meier curves show overall survival in both control (dashed) and test (solid) groups. Over the 60-month follow-up period, the survival difference is not statistically significant (P = .12). Also

    Kaplan-Meier curves show overall survival in both control (dashed) and test (solid) groups. Over the 60-month follow-up period, the survival difference is not statistically significant (P = .12). Also shown is the number of patients at risk in each population at annual increments over 5 years.

  • Image Result
    Curves show percentage of patients in control (dashed) and test (solid) groups free from aneurysm-related mortality. Over the 60-month follow-up period, the aneurysm-related survival difference is not

    Curves show percentage of patients in control (dashed) and test (solid) groups free from aneurysm-related mortality. Over the 60-month follow-up period, the aneurysm-related survival difference is not statistically different (P = .8). Also shown is the number of patients at risk in each population at annual increments over 5 years.

  • Image Result
    Curves show percentage of patients in control (dashed) and test (solid) groups free from major adverse events (MAE). Over the 60-month follow-up period, the freedom from MAE is significantly greater f

    Curves show percentage of patients in control (dashed) and test (solid) groups free from major adverse events (MAE). Over the 60-month follow-up period, the freedom from MAE is significantly greater for the test group compared with the control group (P < .001). Also shown is the number of patients at risk in each population at annual increments over 5 years.

 Competition of interest: Dr Matsumura has been a paid consultant, clinical investigator, and/or received support from Abbott, Bard, Cook, Cordis, ev3, Medtronic, and WL Gore.

PII: S0741-5214(07)00060-2

doi: 10.1016/j.jvs.2007.01.044

Journal of Vascular Surgery
Volume 45, Issue 5 , Pages 885-890 , May 2007