Journal of Vascular Surgery
Volume 45, Issue 1 , Pages 40-46 , January 2007

Association of obesity and metabolic syndrome with the severity and outcome of intermittent claudication

  • Jonathan Golledge, MChir, MA, FRCS, FRACS

      Affiliations

    • Vascular Biology Unit, James Cook University, Townsville, Queensland, Australia
    • Townsville Hospital, Townsville, Queensland, Australia.
    • Corresponding Author InformationReprint requests: Jonathan Golledge, MChir, MA, FRCS, FRACS, The Vascular Biology Unit, James Cook University, Townsville, Queensland 4811, Australia.
    • J.G. and A.L. contributed equally to this work.
  • ,
  • Anthony Leicht, PhD

      Affiliations

    • Institute of Sport and Exercise Science, James Cook University, Townsville, Queensland, Australia
    • J.G. and A.L. contributed equally to this work.
  • ,
  • Robert G. Crowther, BSc(hons)

      Affiliations

    • Institute of Sport and Exercise Science, James Cook University, Townsville, Queensland, Australia
  • ,
  • Paula Clancy, PhD

      Affiliations

    • Vascular Biology Unit, James Cook University, Townsville, Queensland, Australia
  • ,
  • Warwick L. Spinks, PhD

      Affiliations

    • Institute of Sport and Exercise Science, James Cook University, Townsville, Queensland, Australia
  • ,
  • Francis Quigley, MS

      Affiliations

    • Townsville Hospital, Townsville, Queensland, Australia.

Received 2 August 2006 ,Accepted 1 September 2006.

  • Image Result

    Scatterplots showing the relationship between waist-hip ratio or serum adiponectin and the severity of lower limb artery disease. Waist-hip ratio was correlated with ankle-brachial pressure index (ABP

    Scatterplots showing the relationship between waist-hip ratio or serum adiponectin and the severity of lower limb artery disease. Waist-hip ratio was correlated with ankle-brachial pressure index (ABPI) (a, r = −0.41; P = .001). Serum adiponectin was correlated with ABPI (b, r = 0.31; P = .01), maximum walking distance (MWD) (c, r = 0.26; P = .04), and initial claudication distance (ICD) (d, r = 0.36; P = .005).

 Supported by funding from the National Health and Medical Research Council (279408/379600), National Institutes of Health (R01 HL080010-01), and James Cook University.CME article

PII: S0741-5214(06)01630-2

doi: 10.1016/j.jvs.2006.09.006

Journal of Vascular Surgery
Volume 45, Issue 1 , Pages 40-46 , January 2007