Journal of Vascular Surgery
Volume 44, Issue 6 , Pages 1363-1368 , December 2006

The evolving impact of microfabrication and nanotechnology on stent design

  • Jeffrey M. Caves, PhD

      Affiliations

    • Departments of Biomedical Engineering, Georgia Institute of Technology and Emory University School of Medicine, Atlanta, Ga
  • ,
  • Elliot L. Chaikof, MD, PhD

      Affiliations

    • Departments of Biomedical Engineering, Georgia Institute of Technology and Emory University School of Medicine, Atlanta, Ga
    • Department of Surgery, Emory University School of Medicine, Atlanta, Ga
    • School of Chemical and Biomolecular Engineering, Georgia Institute of Technology, Atlanta, Ga.
    • Corresponding Author InformationCorrespondence: Elliot L. Chaikof, MD, PhD, 101 Woodruff Circle, Room 5105, Emory University, Atlanta, GA 30322.

Received 21 July 2006 ,Accepted 6 August 2006.

References 

  1. Selvin E, Erlinger TP. Prevalence of and risk factors for peripheral arterial disease in the United States: Results from the national health and nutrition examination survey, 1999-2000. Circulation. 2004;110:738–743
  2. Garcia LA. Epidemiology and pathophysiology of lower extremity peripheral arterial disease. J Endovasc Ther. 2006;13(Suppl 2):II3–II9
  3. Centers for Disease Control and Prevention. Lower extremity disease among persons aged > or =40 years with and without diabetes—United States, 1999-2002. MMWR Morb Mortal Wkly Rep. 2005;54:1158–1160
  4. Centers for Disease Control and Prevention. Mobility limitation among persons aged > or =40 years with and without diagnosed diabetes and lower extremity disease–United States, 1999-2002. MMWR Morb Mortal Wkly Rep. 2005;54:1183–1186
  5. McDermott MM, Guralnik JM, Ferrucci L, Criqui MH, Greenland P, Tian L, et al. Functional decline in lower-extremity peripheral arterial disease: Associations with comorbidity, gender, and race. J Vasc Surg. 2005;42:1131–1137
  6. Grimm J, Muller-Hulsbeck S, Jahnke T, Hilbert C, Brossmann J, Heller M. Randomized study to compare PTA alone versus PTA with Palmaz stent placement for femoropopliteal lesions. J Vasc Interv Radiol. 2001;12:935–942
  7. Wissgott C, Scheinert D, Rademaker J, Werk M, Schedel H, Steinkamp HJ. Treatment of long superficial femoral artery occlusions with excimer laser angioplasty: long-term results after 48 months. Acta Radiol. 2004;45:23–29
  8. Zeller T, Rastan A, Schwarzwalder U, Frank U, Burgelin K, Amantea P, et al. Midterm results after atherectomy-assisted angioplasty of below-knee arteries with use of the Silverhawk device. J Vasc Interv Radiol. 2004;15:1391–1397
  9. Laird JR. Limitations of percutaneous transluminal angioplasty and stenting for the treatment of disease of the superficial femoral and popliteal arteries. J Endovasc Ther. 2006;13(Suppl 2):II30–II40
  10. Muradin GS, Bosch JL, Stijnen T, Hunink MG. Balloon dilation and stent implantation for treatment of femoropopliteal arterial disease: meta-analysis. Radiology. 2001;221:137–145
  11. Schillinger M, Exner M, Mlekusch W, Haumer M, Rumpold H, Ahmadi R, et al. Endovascular revascularization below the knee: 6-month results and predictive value of C-reactive protein level. Radiology. 2003;227:419–425
  12. Duda SH, Bosiers M, Lammer J, Scheinert D, Zeller T, Tielbeek A, et al. Sirolimus-eluting versus bare nitinol stent for obstructive superficial femoral artery disease: the SIROCCO II trial. J Vasc Interv Radiol. 2005;16:331–338
  13. Stone GW, Ellis SG, Cox DA, Hermiller J, O’Shaughnessy C, Mann JT, et al. One-year clinical results with the slow-release, polymer-based, paclitaxel-eluting taxus stent: The TAXUS-IV trial. Circulation. 2004;109:1942–1947
  14. Moses JW, Leon MB, Popma JJ, Fitzgerald PJ, Holmes DR, O’Shaughnessy C, et al. Sirolimus-eluting stents versus standard stents in patients with stenosis in a native coronary artery. N Engl J Med. 2003;349:1315–1323
  15. Henry M, Polydorou A, Henry I, Ad Polydorou I, Hugel IM, Anagnostopoulou S. Angioplasty and stenting of extracranial vertebral artery stenosis. Int Angiol. 2005;24:311–324
  16. Schillinger M, Sabeti S, Loewe C, Dick P, Amighi J, Mlekusch W, et al. Balloon angioplasty versus implantation of nitinol stents in the superficial femoral artery. N Engl J Med. 2006;354:1879–1888
  17. Iakovou I, Schmidt T, Bonizzoni E, Ge L, Sangiorgi GM, Stankovic G, et al. Incidence, predictors, and outcome of thrombosis after successful implantation of drug-eluting stents. JAMA. 2005;293:2126–2130
  18. Farb A, Burke AP, Kolodgie FD, Virmani R. Pathological mechanisms of fatal late coronary stent thrombosis in humans. Circulation. 2003;108:1701–1706
  19. Kotani J, Awata M, Nanto S, Uematsu M, Oshima F, Minamiguchi H, et al. Incomplete neointimal coverage of sirolimus-eluting stents: angioscopic findings. J Am Coll Cardiol. 2006;47:2108–2111
  20. Virmani R, Guagliumi G, Farb A, Musumeci G, Grieco N, Motta T, et al. Localized hypersensitivity and late coronary thrombosis secondary to a sirolimus-eluting stent: should we be cautious?. Circulation. 2004;109:701–705
  21. Aoki J, Ong AT, Rodriguez Granillo GA, McFadden EP, van Mieghem CA, Valgimigli M, et al. “Full metal jacket” (stented length > or =64 mm) using drug-eluting stents for de novo coronary artery lesions. Am Heart J. 2005;150:994–999
  22. Finkelstein A, McClean D, Kar S, Takizawa K, Varghese K, Baek N, et al. Local drug delivery via a coronary stent with programmable release pharmacokinetics. Circulation. 2003;107:777–784
  23. Murali M, Yeo SH. Rapid biocompatible micro device fabrication by micro electro-discharge machining. Biomed Microdevices. 2004;6:41–45
  24. Takahata K, Gianchandani KT. A planar approach for manufacturing cardic stents: design, fabrication, and mechanical evaluation. J Microelectromech Syst. 2004;13:933–939
  25. Reed ML, Wu C, Kneller J, Watkins S, Vorp DA, Nadeem A, et al. Micromechanical devices for intravascular drug delivery. J Pharm Sci. 1998;87:1387–1394
  26. Henry S, McAllister DV, Allen MG, Prausnitz MR. Microfabricated microneedles: a novel approach to transdermal drug delivery. J Pharm Sci. 1998;87:922–925
  27. McAllister DV, Wang PM, Davis SP, Park JH, Canatella PJ, Allen MG, et al. Microfabricated needles for transdermal delivery of macromolecules and nanoparticles: fabrication methods and transport studies. Proc Natl Acad Sci U S A. 2003;100:13755–13760
  28. Miller DC, Thapa A, Haberstroh KM, Webster TJ. Endothelial and vascular smooth muscle cell function on poly(lactic-co-glycolic acid) with nano-structured surface features. Biomaterials. 2004;25:53–61
  29. Miller DC, Haberstroh KM, Webster TJ. Mechanism(s) of increased vascular cell adhesion on nanostructured poly(lactic-co-glycolic acid) films. J Biomed Mater Res A. 2005;73:476–484
  30. Liu DM, Troczynski T, Tseng WJ. Water-based sol-gel synthesis of hydroxyapatite: process development. Biomaterials. 2001;22:1721–1730
  31. Liu DM, Yang Q, Troczynski T. Sol-gel hydroxyapatite coatings on stainless steel substrates. Biomaterials. 2002;23:691–698
  32. Areva S, Paldan H, Peltola T, Narhi T, Jokinen M, Linden M. Use of sol-gel-derived titania coating for direct soft tissue attachment. J Biomed Mater Res A. 2004;70:169–178
  33. Guzman LA, Labhasetwar V, Song C, Jang Y, Lincoff AM, Levy R, et al. Local intraluminal infusion of biodegradable polymeric nanoparticles (A novel approach for prolonged drug delivery after balloon angioplasty). Circulation. 1996;94:1441–1448
  34. Labhasetwar V, Song C, Humphrey W, Shebuski R, Levy RJ. Arterial uptake of biodegradable nanoparticles: effect of surface modifications. J Pharm Sci. 1998;87:1229–1234
  35. Lanza GM, Yu X, Winter PM, Abendschein DR, Karukstis KK, Scott MJ, et al. Targeted antiproliferative drug delivery to vascular smooth muscle cells with a magnetic resonance imaging nanoparticle contrast agent: implications for rational therapy of restenosis. Circulation. 2002;106:2842–2847
  36. Wickline SA, Neubauer AM, Winter P, Caruthers S, Lanza G. Applications of nanotechnology to atherosclerosis, thrombosis, and vascular biology. Arterioscler Thromb Vasc Biol. 2006;26:435–441
  37. Uwatoku T, Shimokawa H, Abe K, Matsumoto Y, Hattori T, Oi K, et al. Application of nanoparticle technology for the prevention of restenosis after balloon injury in rats. Circ Res. 2003;92:e62–e69
  38. Kolodgie FD, John M, Khurana C, Farb A, Wilson PS, Acampado E, et al. Sustained reduction of in-stent neointimal growth with the use of a novel systemic nanoparticle paclitaxel. Circulation. 2002;106:1195–1198

 Kenneth Ouriel, MD, Review Section Editor

 Competition of interest: none.

PII: S0741-5214(06)01511-4

doi: 10.1016/j.jvs.2006.08.046

Journal of Vascular Surgery
Volume 44, Issue 6 , Pages 1363-1368 , December 2006