« Previous Next » Journal of Vascular Surgery
Volume 43, Issue 3 , Pages 570-576 , March 2006

Biomechanical properties of ruptured versus electively repaired abdominal aortic aneurysm wall tissue

Elena S. Di Martino, PhD
- Department of Surgery, University of Pittsburgh, Pittsburgh, PA
- Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA
- McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA
Ajay Bohra, MS
- Department of Surgery, University of Pittsburgh, Pittsburgh, PA
Jonathan P. Vande Geest, BS
- Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA
Navyash Gupta, MD
- Department of Surgery, University of Pittsburgh, Pittsburgh, PA
Michel S. Makaroun, MD
- Department of Surgery, University of Pittsburgh, Pittsburgh, PA
David A. Vorp, PhD
- Department of Surgery, University of Pittsburgh, Pittsburgh, PA
- Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA
- McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA
- Reprint requests: David A. Vorp, PhD, University of Pittsburgh, Division of Vascular Surgery, Department of Surgery and Bioengineering, Vascular Bioengineering Research Laboratory, McGowan Institute for Regenerative Medicine, Suite 200, 100 Technology Dr, Pittsburgh, PA 15219

Received 3 July 2005 ,Accepted 30 October 2005.

The location of harvest for the abdominal aortic aneurysm (AAA) tissue is indicated on a schematic representation of an aneurysm.

The location of harvest for the abdominal aortic aneurysm (AAA) tissue is indicated on a schematic representation of an aneurysm.
- Full-Size Image
- Download to PowerPoint
Stress-stretch curve for one generic tensile test. UTS, Ultimate tensile strength; TM_max, maximum tangential modulus; TM₁₀₀, tangential modulus corresponding to a pressure of 100 mm Hg; UStr, ultimate

Stress-stretch curve for one generic tensile test. UTS, Ultimate tensile strength; TM_max, maximum tangential modulus; TM₁₀₀, tangential modulus corresponding to a pressure of 100 mm Hg; UStr, ultimate stretch.
- Full-Size Image
- Download to PowerPoint
Correlation between the diameter of the aneurysm and the ultimate tensile strength (UTS). The Spearman correlation coefficient showed no statistical significance (P = .55). The regression line is show

Correlation between the diameter of the aneurysm and the ultimate tensile strength (UTS). The Spearman correlation coefficient showed no statistical significance (P = .55). The regression line is shown for all data in the plot. eAAA, elective abdominal aortic aneurysm; rAAA, ruptured abdominal aortic aneurysm.
- Full-Size Image
- Download to PowerPoint
Correlation between tissue thickness and ultimate tensile strength (UTS). The regression line is shown for all data in the plot. eAAA, elective abdominal aortic aneurysm; rAAA, ruptured abdominal aort

Correlation between tissue thickness and ultimate tensile strength (UTS). The regression line is shown for all data in the plot. eAAA, elective abdominal aortic aneurysm; rAAA, ruptured abdominal aortic aneurysm.
- Full-Size Image
- Download to PowerPoint
Correlation between maximum tangential modulus (TMmax) and ultimate tensile strength (UTS). The regression line is shown for all data in the plot.

Correlation between maximum tangential modulus (TM_max) and ultimate tensile strength (UTS). The regression line is shown for all data in the plot.
- Full-Size Image
- Download to PowerPoint

This research was funded in part by National Institutes of Health grant RO1HL060670 (D.A.V.).Competition of interest: none.Preliminary data presented at the Biomedical Engineering Society Fall meeting, Philadelphia, PA, October 13-16, 2004.

PII: S0741-5214(05)01921-X

doi: 10.1016/j.jvs.2005.10.072

« Previous Next » Journal of Vascular Surgery
Volume 43, Issue 3 , Pages 570-576 , March 2006